Advertisement

Journal of Autism and Developmental Disorders

, Volume 46, Issue 6, pp 2267–2269 | Cite as

Case Report: Resolution of Severe Sexual Aggression in a Developmentally Disabled Adolescent During Leuprolide Acetate Use

  • Cara Fosdick
  • Sarah Mohiuddin
Letter to the Editor

Introduction

Aggressive sexual behavior carries particular challenges for developmentally disabled individuals (Dewinter et al. 2013; Realmuto and Ruble 1999; Lindsay 2002; Patel et al. 2010; Ruble and Dalrymple 1993). In the setting of developmental disability, some sexual behavior can be socially problematic, but not clearly intrusive or aggressive. For example, taking off one’s own clothes or touching private parts in public can occur during the course of development in a young, neurotypical child, and may appear later or for longer in an individual with intellectual disability. Combined with impulsivity and communication difficulties, it can be difficult to delineate sexual aggression from impulsive aggression, hypersexuality, or other problematic sexual behaviors, making sexual aggression difficult to define in this population. (Dewinter et al. 2013; Realmuto and Ruble 1999).

How to most appropriately intervene with sexual aggression can be an ethically complicated question in a...

Keywords

Testosterone Aripiprazole Intellectual Disability Physical Aggression Atomoxetine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Author Contributions

Both Dr. Fosdick and Dr. Mohiuddin contributed to the writing and research involved in this case report.

Compliance with Ethical Standards

Conflict of interest

None.

References

  1. Briken, P., Hill, A., & Berner, W. (2003). Pharmacotherapy of paraphilias with long-acting agonists of luteinizing hormone-releasing hormone: A systematic review. Journal of Clinical Psychiatry, 64(8), 890–897.CrossRefPubMedGoogle Scholar
  2. Deepmala, M., & Agrawal, M. (2014). Use of propranolol for hypersexual behavior in an adolescent with autism. Annals of Pharmacotherapy, 48(10), 1385–1388.CrossRefPubMedGoogle Scholar
  3. Dewinter, J., Vermeiren, R., Vanwesenbeeck, I., & Van Nieuwenhuizen, C. (2013). Autism and normative sexual development: A narrative review. Journal of Clinical Nursing, 22(23–24), 3467–3483.CrossRefPubMedGoogle Scholar
  4. Guay, D. (2009). Drug treatment of paraphilic and nonparaphilic sexual disorders. Clinical Therapeutics, 31(1), 1–31.CrossRefPubMedGoogle Scholar
  5. Jones, M., & Okere, K. (2008). Treatment of hypersexual behavior with oral estrogen in an autistic male. Southern Medical Journal, 101(9), 960–969.CrossRefGoogle Scholar
  6. Koo, K., Shim, G., Park, H., Rha, K., Choi, Y., Chung, B., et al. (2013). Treatment outcomes of chemical castration on Korean sex offenders. Journal of Forensic and Legal Medicine, 20(6), 563–566.CrossRefPubMedGoogle Scholar
  7. Levitsky, A., & Owens, N. (1999). Pharmacologic treatment of hypersexuality and paraphilias in nursing home residents. Journal of the American Geriatrics Society, 47(2), 231–234.CrossRefPubMedGoogle Scholar
  8. Lindsay, W. (2002). Research and literature on sex offenders with intellectual and developmental disabilities. Journal of Intellectual Disability Research, 46(Suppl 1), 74–85.CrossRefPubMedGoogle Scholar
  9. Patel, D., Greydanus, D., Calles, J., & Pratt, H. (2010). Developmental disabilities across the lifespan. Disease-A-Month, 56(6), 304–397. doi: 10.1016/j.disamonth.2010.02.001.CrossRefPubMedGoogle Scholar
  10. Poelmans, G., Franke, B., Pauls, D., Glennon, J., & Buitelaar, K. (2013). AKAPs integrate genetic findings for autism spectrum disorders. Translational Psychiatry, 3, e270. doi: 10.1038/tp.2013.48.CrossRefPubMedPubMedCentralGoogle Scholar
  11. Realmuto, G., & Ruble, L. (1999). Sexual behaviors in autism: Problems of definition and management. Journal of Autism and Developmental Disorders, 29(2), 121–127.CrossRefPubMedGoogle Scholar
  12. Ruble, L., & Dalrymple, N. (1993). Social/sexual awareness of persons with autism: A Parental perspective. Archives of Sexual Behavior, 22(3), 229–240.CrossRefPubMedGoogle Scholar
  13. Schober, J., Kuhn, P., Kovacs, P., Earle, J., Byrne, P., & Fries, R. (2005). Leuprolide acetate suppresses pedophilic urges and arousability. Archives of Sexual Behavior, 34(6), 691–705.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Child and Adolescent PsychiatryUniversity of MichiganAnn ArborUSA

Personalised recommendations