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Journal of Autism and Developmental Disorders

, Volume 43, Issue 4, pp 794–806 | Cite as

The Modality Shift Experiment in Adults and Children with High Functioning Autism

  • Diane L. Williams
  • Gerald Goldstein
  • Nancy J. Minshew
Original Article

Abstract

This study used the modality shift experiment, a relatively simple reaction time measure to visual and auditory stimuli, to examine attentional shifting within and across modalities in 33 children and 42 adults with high-functioning autism as compared to matched numbers of age- and ability-matched typical controls. An exaggerated “modality shift effect” relative to the TD children occurred for the children with autism in conditions involving the reaction time when shifting from sound to light but not from light to sound. No exaggerated MSE was found for the adults with autism; rather, their responses were characterized by a generalized slowness relative to the adults with TD. These results suggest a lag in maturational development in autism in basic information processing mechanisms.

Keywords

Autism Attentional shifting Speed of processing Perceptual development 

Notes

Acknowledgments

This work was supported by the National Institute of Neurological Disorders and Stroke (NINDS) [grant number NS33355]; the National Institute of Child Health and Human Development (NICHD) [HD35469, a Collaborative Program of Excellence in Autism (CPEA), to N.J.M.]; the National Institute of Child Health and Human Development [HD055748, an Autism Center of Excellence, to N.J.M.]; and, the National Institute on Deafness and other Communication Disorders (NIDCD) [K23DC006691 to D.L.W.]. The Medical Research Service, Department of Veterans Affairs is also acknowledged for support of this research. The authors are grateful to the participants and their families who generously gave of their time for this research.

References

  1. Allen, G., & Courchesne, E. (2001). Attention function and dysfunction in autism. Frontiers in Bioscience, 6, d105–119.PubMedCrossRefGoogle Scholar
  2. Bauman, M. L. (1992). Motor dysfunction in autism. In A. B. Joseph & R. R. Young (Eds.), Movement disorders in neurology and neuropsychiatry (pp. 659–661). Boston: Blackwell Scientific.Google Scholar
  3. Behrmann, M., Thomas, C., & Humphreys, K. (2006). Seeing it differently: Visual processing in autism. Trends in Cognitive Sciences, 10, 258–264.PubMedCrossRefGoogle Scholar
  4. Bogte, H., Flamma, B., van der Meere, J., & van Engeland, H. (2008). Cognitive flexibility in adults with high functioning autism. Journal of Clinical and Experimental Neuropsychology, 30, 33–41.PubMedCrossRefGoogle Scholar
  5. Boucher, J., & Bowler, D. M. (2009). Memory in autism. Cambridge, UK: Cambridge University Press.Google Scholar
  6. Bryson, S. E., Zwaigenbaum, L., Brian, J., Roberts, W., Szatmari, P., et al. (2007). A prospective case series of high-risk infants who developed autism. Journal of Autism and Developmental Disorders, 37, 12–24.PubMedCrossRefGoogle Scholar
  7. Cohen, R., & Rist, F. (1992). The modality shift effect. Further explorations at the crossroads. Annals of the New York Academy of Sciences, 658, 163–181.PubMedCrossRefGoogle Scholar
  8. Courchesne, E., Townsend, J., Akshoomoff, N. A., Saitoh, O., Yeung-Courchesne, R., Lincoln, A. J., et al. (1994). Impairment in shifting attention in autistic and cerebellar patients. Behavioral Neuroscience, 108, 848–865.PubMedCrossRefGoogle Scholar
  9. Frith, U. (1989). Autism: Explaining the enigma. Oxford: Blackwell.Google Scholar
  10. Frith, U., & Happé, F. (1994). Autism: beyond ‘‘theory of mind’’. Cognition, 50, 115–132.PubMedCrossRefGoogle Scholar
  11. Frith, U., & Hill, E. (2003). Autism: Mind and brain. New York: Oxford University Press.Google Scholar
  12. Gillberg, C., & Coleman, M. (1992). The biology of the autistic syndromes (2nd ed.). London: MacKeith Press.Google Scholar
  13. Gomot, M., Bernard, F. A., Davis, M. H., Belmonte, M. K., Ashwin, C., Bullmore, E. T., et al. (2006). Change detection in children with autism: An auditory event-related fMRI study. NeuroImage, 29, 474–484.CrossRefGoogle Scholar
  14. Happé, F. (1999). Autism: Cognitive deficit or cognitive style? Trends in Cognitive Sciences, 3, 216–222.PubMedCrossRefGoogle Scholar
  15. Happé, F., & Frith, U. (2006). The weak coherence account: Detailed-focused cognitive style in autism spectrum disorders. Journal of Autism and Developmental Disorders, 36, 5–25.PubMedCrossRefGoogle Scholar
  16. Hillock, A. R., Powers, A. R., & Wallace, M. T. (2011). Binding of sights and sounds: Age-related changes in multisensory temporal processing. Neuropsychologia, 49, 461–467.PubMedCrossRefGoogle Scholar
  17. Hughes, C. (1996). Brief report: Planning problems in autism at the level of motor control. Journal of Autism and Developmental Disorders, 26, 99–107.PubMedCrossRefGoogle Scholar
  18. Ibanez, L. V., Messinger, D. S., Newell, L., Lambert, B., & Sheskin, M. (2008). Visual disengagement in the infant siblings of children with an autism spectrum disorder (ASD). Autism, 12, 473–486.PubMedCrossRefGoogle Scholar
  19. Just, M. A., Cherkassky, V. L., Keller, T. A., & Minshew, N. J. (2004). Cortical activation and synchronization during sentence comprehension in high-functioning autism: Evidence of underconnectivity. Brain, 127, 1811–1821.PubMedCrossRefGoogle Scholar
  20. Landry, R., & Bryson, S. E. (2004). Impaired disengagement of attention in young children with autism. Journal of Child Psychology and Psychiatry, 45, 1115–1122.PubMedCrossRefGoogle Scholar
  21. LeCouteur, A., Rutter, M., Lord, C., Rios, P., Robertson, S., Holdgrafer, M., et al. (1989). Autism diagnostic interview: A standardized investigator-based instrument. Journal of Autism and Developmental Disorders, 19, 363–387.CrossRefGoogle Scholar
  22. Leekam, S. R., Hunnisett, E., & Moore, C. (1998). Targets and cues: Gaze-following in children with autism. The Journal of Child Psychology and Psychiatry, 39, 951–962.CrossRefGoogle Scholar
  23. Lewkowicz, D. J., & Lickliter, R. (Eds.). (1994). The development of intersensory perception: Comparative perspectives. Hillside, NJ: Lawrence Erlbaum Associates, Inc.Google Scholar
  24. Lord, C., Risi, S., Lambrecht, L., Cook, E. H, Jr, Leventhal, B. L., DiLavore, P. C., et al. (2000). The Autism Diagnostic Observation Schedule-Generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223.PubMedCrossRefGoogle Scholar
  25. Lord, C., Rutter, M., Goode, S., Heemsbergen, J., Jordan, H., Mawhood, L., et al. (1989). Autism Diagnostic Observation Schedule: A standardized observation of communicative and social behavior. Journal of Autism and Developmental Disorders, 19, 185–212.PubMedCrossRefGoogle Scholar
  26. Lord, C., Rutter, M., & LeCouteur, A. L. (1994). Autism diagnostic interview revised a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685.PubMedCrossRefGoogle Scholar
  27. Mannuzza, S., Kietzman, M. L., Berenhaus, I. J., Ramsey, P. H., Zubin, J., & Sutton, S. (1984). The modality shift effect in schizophrenia: Fact or artifact. Biological Psychiatry, 19, 1317–1331.PubMedGoogle Scholar
  28. Minshew, N. J., & Goldstein, G. (1992). Autism: A distributed neural network deficit? Journal of Clinical and Experimental Neuropsychology, 15, 56.Google Scholar
  29. Minshew, N. J., Goldstein, G., & Siegel, D. J. (1997). Neuropsychologic functioning in autism: profile of a complex information processing disorder. Journal of the International Neuropsychological Society, 3, 303–316.PubMedGoogle Scholar
  30. Minshew, N. J., Luna, B., & Sweeney, J. A. (1999). Oculomotor evidence for neocortical systems but not cerebelllar dysfunction in autism. Neurology, 23, 917–922.CrossRefGoogle Scholar
  31. Mottron, L., & Burack, J. (2001). Enhanced perceptual functioning in the development of autism. In J. Burack, T., Charman, N., Yirmiya, & P. R. Zelazo (Eds.), The development of autism (pp. 131–148). Mahway, NJ: Lawrence Erlbaum.Google Scholar
  32. Mottron, L., Dawson, M., Soulières, I., Hubert, B., & Burack, J. (2006). Enhanced perceptual functioning in autism: An update, and eight principles of autistic perception. Journal of Autism and Developmental Disorders, 36, 27–43.PubMedCrossRefGoogle Scholar
  33. Nadig, A. S., Ozonoff, S., Young, G. S., Rozga, A., Sigman, M., et al. (2007). A prospective study of response-to-name in infants at risk of autism. Archives of Pediatrics and Adolescent Medicine, 161, 378–383.PubMedCrossRefGoogle Scholar
  34. Oliveras-Rentas, R. E., Kenworthy, L., Roberson, R. B., Martin, A., & Wallace, G. L. (2011). WISC-IV profile in high-functioning autism spectrum disorders: Impaired processing speed is associated with increased autism communication symptoms and decreased adaptive communication abilities. Journal of Autism and Developmental Disorders. Advance online publication,. doi: 10.1007/s10803-011-1289-7.Google Scholar
  35. Pascualvaca, D. M., Fantie, B. D., Papageorgiou, M., & Mirsky, A. F. (1998). Attentional capacities in children with autism: Is there a general deficit in shifting focus. Journal of Autism and Developmental Disabilities, 28, 467–478.CrossRefGoogle Scholar
  36. Patten, E., & Watson, L. R. (2011). Interventions targeting attention in young children with autism. American Journal of Speech-Language Pathology, 20, 60–69.PubMedCrossRefGoogle Scholar
  37. Poljac, E., Simon, S., Ringlever, L., Kalcik, D., Groen, W. B., Buitelaar, J. K., et al. (2010). Impaired task switching performance in children with dyslexia but not in children with autism. Quarterly Journal of Experimental Psychology, 63, 401–416.CrossRefGoogle Scholar
  38. Reed, P., & McCarthy, J. (2012). Cross-modal attention-switching is impaired in autism spectrum disorders. Journal of Autism and Developmental Disorders, 42, 947–953.PubMedCrossRefGoogle Scholar
  39. Reitan, R. M., & Wolfson, D. (1993). Halstead-Reitan neuropsychological test battery: Theory and clinical interpretation. Tucson, AZ: Neuropsychology Press.Google Scholar
  40. Rist, F., & Cohen, R. (1991). Sequential effects in the reaction times of schizophrenics: crossover and modality shift effects. In S. R. Steinhauer, J. H. Gruzelier, & J. Zubin (Eds.), Handbook of Schizophrenia (Vol. 5, pp. 241–271). Amsterdam: Elsevier.Google Scholar
  41. Smith, I. M., & Bryson, S. E. (1994). Imitation and action in autism: A critical review. Psychological Bulletin, 116, 259–273.PubMedCrossRefGoogle Scholar
  42. Sternberg, S. (1969). Discovery of processing stages: Extensions of Donder’s method. Acta Psychologica, 8, 276–315.CrossRefGoogle Scholar
  43. Stoet, G., & López, B. (2011). Task switching abilities in children with autism spectrum disorder. European Journal of Developmental Psychology, 8, 244–260.CrossRefGoogle Scholar
  44. Sutton, S., Hakerem, G., Zubin, J., & Portnoy, M. (1961). The effect of shift of sensory modality on serial reaction time: A comparison of schizophrenics and normals. American Journal of Psychology, 74, 224–232.CrossRefGoogle Scholar
  45. Travers, B. G., Klinger, M. R., & Klinger, L. G. (2011). Attention and working memory in ASD. In D. A. Fein (Ed.), The neuropsychology of autism (pp. 161–184). NY: Oxford University Press.Google Scholar
  46. Wainwright-Sharp, J. W., & Bryson, S. E. (1993). Visual orienting deficits in high functioning people with autism. Journal of Autism and Developmental Disorders, 23, 1–13.PubMedCrossRefGoogle Scholar
  47. Wechsler, D. (1991). Wechsler intelligence scale for children (3rd ed.). San Antonio, TX: Psychological Corporation.Google Scholar
  48. Wechsler, D. (1997). Wechsler adult intelligence scale (3rd ed.). San Antonio, TX: Psychological Corporation.Google Scholar
  49. Wechsler, D. (2003). Wechsler intelligence scale for children-fourth edition (WISC-IV). San Antonio, TX: Psychological Corporation.Google Scholar
  50. Williams, D. L., Goldstein, G., & Minshew, N. J. (2006). Neuropsychologic functioning in children with autism: Further evidence of disordered complex information processing. Child Neuropsychology, 12, 279–298.PubMedCrossRefGoogle Scholar
  51. Zubin, J. (1975). Problem of attention in schizophrenia. In M. Kietzman, S. Sutton, & J. Zubin (Eds.), Experimental approaches to psychopathology (pp. 139–166). New York: Academic Press.Google Scholar
  52. Zwaigenbaum, L., Bryson, S., Rogers, T., Roberts, W., Brian, J., & Szatmari, P. (2005). Behavioral manifestations of autism in the first year of life. International Journal of Developmental Neuroscience, 23, 143–152.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Diane L. Williams
    • 1
  • Gerald Goldstein
    • 2
  • Nancy J. Minshew
    • 3
  1. 1.Department of Speech-Language PathologyDuquesne UniversityPittsburghUSA
  2. 2.VA Pittsburgh Healthcare System and Department of PsychiatryUniversity of Pittsburgh School of MedicinePittsburghUSA
  3. 3.Departments of Psychiatry and NeurologyUniversity of Pittsburgh School of MedicinePittsburghUSA

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