Using the Autism Diagnostic Interview-Revised and the Autism Diagnostic Observation Schedule-Generic for the Diagnosis of Autism Spectrum Disorders in a Greek Sample with a Wide Range of Intellectual Abilities
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We studied the interrelationship between the Autism Diagnostic Observation Schedule-Generic (ADOS-G), the Autism Diagnostic Interview-Revised (ADI-R) and DSM-IV clinical diagnosis, in a Greek sample of 77 children and adolescents, referred for the assessment of a possible pervasive developmental disorder (PDD) and presenting a wide range of cognitive abilities. The agreement of the ADOS-G and the ADI-R with the clinical diagnosis was estimated as satisfactory and moderate, respectively, while both instruments presented with excellent sensitivity for the diagnosis of autistic disorder along with satisfactory specificity. ADOS-G/ADI-R agreement was estimated as fair. Our results confirm the discriminant validity of ADI-R and ADOS-G in diagnosing pervasive developmental disorders in children and adolescents with a wide range of intellectual abilities.
KeywordsADI-R ADOS-G Autism spectrum disorders Diagnosis
We wish to thank the parents and children that participated in this study. We also thank our colleagues Margarita Bouranta, psychologist, Sofia Giannopoulou speech therapist, Dimitrios Arvanitis and Konstantina Argyrou occupational therapists, and Vassiliki Dre health visitor who contributed to the clinical assessment of our patients. We also thank Debbie Spain, Cognitive Behavioral Therapist, for the careful editing of the final manuscript.
- Association, American Psychiatric. (1994). Diagnostic and statistical manual of mental disorders (DSM-IV). Washington, DC: American Psychiatric Press Inc.Google Scholar
- Association, American Psychiatric. (2004). Diagnostic and statistical manual of mental disorders forth edition-text revision (DSM-IV-TR). Washington, DC: American Psychiatric Press Inc.Google Scholar
- Cox, A., Klein, C., Charman, T., Baird, G., Baron-Cohen, S., Swettenham, J., et al. (1999). Autism spectrum disorders at 20 and 42 months of age: Stability of clinical and ADI-R diagnosis. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 40, 719–732. doi: 10.1017/S002196309900400X.PubMedCrossRefGoogle Scholar
- de Bildt, A., Sytema, S., Ketelaars, C., Kraijer, D., Mulder, E., Volkmar, F., et al. (2004). Interrelationship between autism diagnostic observation schedule-generic (ADOS-G), autism diagnostic interview-revised (ADI-R), and the diagnostic and statistical manual of mental disorders (DSM-IV-TR) classification in children and adolescents with mental retardation. Journal of Autism and Developmental Disorders, 34(2), 129–137. doi: 10.1023/B:JADD.0000022604.22374.5f.PubMedCrossRefGoogle Scholar
- Georgas, D. D., Paraskevopoulos, I. N., Bezevegis, I. G., & Giannitsas, N. D. (1997). Greek WISC III Wechsler intelligence scales for children. Athens: Ellinika Grammata.Google Scholar
- Gray, K. M., Tonge, B. J., & Sweety, D. J. (2007). Using the autism diagnostic interview-revised and the autism diagnostic observation schedule with young children with developmental delay: Evaluating diagnostic validity. Journal of Autism and Developmental Disorders. doi: 10.1007/s10803-007-0432-y.
- Le Couteur, A., Haden, G., Hammal, D., & McConachie, H. (2008). Diagnosing autism spectrum disorders in pre-school children using two standardized assessment instruments: The ADI-R and the ADOS. Journal of Autism and Developmental Disorders, 38(2), 362–372. doi: 10.1007/s10803-007-0403-3.PubMedCrossRefGoogle Scholar
- Lord, C. (1997). Diagnostic instruments in autism spectrum disorders. In D. Cohen & F. Volkmar (Eds.), Handbook of autism and pervasive developmental disorders (pp. 460–483). New York: Wiley.Google Scholar
- Lord, C., Risi, S., Lambrecht, L., Cook, E., Leventhal, B., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223. doi: 10.1023/A:1005592401947.PubMedCrossRefGoogle Scholar
- Lord, C., Rutter, M., & Le Couteur, Ann. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24(5), 659–685. doi: 10.1007/BF02172145.PubMedCrossRefGoogle Scholar
- Lord, C., Storoschuk, S., Rutter, M., & Pickles, A. (1993). Using the ADI-R to diagnose autism in preschool children. Infant Mental Health Journal, 14(3), 234–252. doi :10.1002/1097-0355(199323)14:3<234::AID-IMHJ2280140308>3.0.CO;2-F.Google Scholar
- Mahoney, W., Szatmari, P., MacLean, J., Bryson, S., Bartolucci, G., Walter, S., et al. (1998). Reliability and accuracy of differentiating pervasive developmental disorders subtypes. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 278–285. doi: 10.1097/00004583-199803000-00012.PubMedCrossRefGoogle Scholar
- Raven, J. C. (1960). Guide to using the standard progressive matrices. London: H. K. Lewis.Google Scholar
- Risi, S., Lord, C., Gotham, K., Corsello, C., Chrysler, C., Szatmari, P., et al. (2006). Combining information from multiple sources in the diagnosis of autism spectrum disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 1094–1103. doi: 10.1097/01.chi.0000227880.42780.0e.PubMedCrossRefGoogle Scholar
- Roid, G. H., & Miller, L. J. (1997). Leiter performance scale-revised manual. Wood Dale, IL: Stoelting.Google Scholar
- Rutter, M., Le Couteur, A., & Lord, C. (2003). Autism diagnostic interview-revised. Los Angeles, CA: Western Psychological Services.Google Scholar
- Volkmar, F., Cook, E., Pomorey, J., Realmuto, G., & Tanguay, P. (1999). Summary of the practice parameters for the assessment and treatment of children, adolescents and adults with autism and other pervasive developmental disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 38(12), 1611–1615.PubMedCrossRefGoogle Scholar
- Wiggins, L. D., & Robins, D. L. Brief report: Excluding the ADI-R behavioural domain improves diagnostic agreement in toddlers. Journal of Autism and Developmental Disorders, in press. doi: 10.1007/s10803-007-0456-3.
- World Health Organisation. (1992). The tenth revision of the International Classification of Disorders and related health problems (ICD-10). WHO: Geneva.Google Scholar