Abstract
Purpose
To determine the distribution of anterior chamber depth (ACD), anterior chamber volume (ACV), and anterior chamber angle (ACA) values in a rural population over 5 years of age using the Pentacam.
Methods
In this cross-sectional study, samples were selected from over 1-year-old inhabitants of two villages in Iran using a multistage cluster sampling approach. All participants underwent the measurement of uncorrected and corrected visual acuity and auto-refraction, retinoscopy, subjective refraction, and slit lamp examination. Finally, corneal imaging was done for all subjects over 5 years of age using the Pentacam.
Results
Of 3851 selected individuals, 3314 participated in the study, of whom 2681 met the inclusion criteria. The mean age of the sample was 36.03 ± 18.5 years (range 6–90 years). The mean ACD, ACA, and ACV values were 3.37 mm (95% CI: 3.37–3.39), 34.82° (95% CI: 34.45–35.2), and 159.17 µL (95% CI: 156–161.36), respectively. The results of multiple linear regression models showed that ACD, ACA, and ACV values reduced with age, and ACD and ACV values were significantly higher in males. ACA and ACV values correlated inversely with central corneal thickness, while the ACA value correlated directly with keratometry and inversely with the ACV value.
Conclusion
This study is one of the few studies in the world showing changes in ACD values in different age groups using the Pentacam. According to the results, aging was associated with a decline in the mean ACD, ACA, and ACV values. These parameters were the largest in patients with emmetropia and smallest in hyperopic subjects.
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References
Cho HK, Kee C (2014) Population-based glaucoma prevalence studies in Asians. Surv Ophthalmol 59:434–447. https://doi.org/10.1016/j.survophthal.2013.09.003
Tham YC, Li X, Wong TY et al (2014) Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology 121:2081–2090. https://doi.org/10.1016/j.ophtha.2014.05.013
Wright C, Tawfik MA, Waisbourd M et al (2016) Primary angle-closure glaucoma: an update. Acta Ophthalmol 94:217–225. https://doi.org/10.1111/aos.12784
Congdon NG, Spaeth GL, Augsburger J et al (1999) A proposed simple method for measurement in the anterior chamber angle: biometric gonioscopy. Ophthalmology 106:2161–2167. https://doi.org/10.1016/s0161-6420(99)90499-2
Yi JH, Hong S, Seong GJ et al (2008) Anterior chamber measurements by Pentacam and AS-OCT in eyes with normal open angles. Korean J Ophthalmol 22:242–245. https://doi.org/10.3341/kjo.2008.22.4.242
Barrett BT, McGraw PV, Murray LA et al (1996) Anterior chamber depth measurement in clinical practice. Optom Vis Sci 73:482–486
Hashemi H, Khabazkhoob M, Mohazzab-Torabi S et al (2016) Anterior chamber angle and anterior chamber volume in a 40- to 64-year-old population. Eye Contact Lens 42:244–249. https://doi.org/10.1097/icl.0000000000000192
Dinc UA, Gorgun E, Oncel B et al (2010) Assessment of anterior chamber depth using Visante optical coherence tomography, slitlamp optical coherence tomography, IOL Master, Pentacam and Orbscan IIz. Ophthalmologica 224:341–346. https://doi.org/10.1159/000313815
Ucakhan OO, Ozkan M, Kanpolat A (2009) Anterior chamber parameters measured by the Pentacam CES after uneventful phacoemulsification in normotensive eyes. Acta Ophthalmol 87:544–548. https://doi.org/10.1111/j.1755-3768.2008.01305.x
Nemeth G, Vajas A, Kolozsvari B et al (2006) Anterior chamber depth measurements in phakic and pseudophakic eyes: Pentacam versus ultrasound device. J Cataract Refract Surg 32:1331–1335. https://doi.org/10.1016/j.jcrs.2006.02.057
He M, Huang W, Zheng Y et al (2008) Anterior chamber depth in elderly Chinese: the Liwan eye study. Ophthalmology 115:1286–1290. https://doi.org/10.1016/j.ophtha.2007.12.003
Rabsilber TM, Khoramnia R, Auffarth GU (2006) Anterior chamber measurements using Pentacam rotating Scheimpflug camera. J Cataract Refract Surg 32:456–459. https://doi.org/10.1016/j.jcrs.2005.12.103
Cheon MH, Sung KR, Choi EH et al (2010) Effect of age on anterior chamber angle configuration in Asians determined by anterior segment optical coherence tomography; clinic-based study. Acta Ophthalmol 88:e205–e210. https://doi.org/10.1111/j.1755-3768.2010.01960.x
Sun JH, Sung KR, Yun SC et al (2012) Factors associated with anterior chamber narrowing with age: an optical coherence tomography study. Invest Ophthalmol Vis Sci 53:2607–2610. https://doi.org/10.1167/iovs.11-9359
Richdale K, Bullimore MA, Zadnik K (2008) Lens thickness with age and accommodation by optical coherence tomography. Ophthalmic Physiol Opt 28:441–447. https://doi.org/10.1111/j.1475-1313.2008.00594.x
Wendt M, Croft MA, McDonald J et al (2008) Lens diameter and thickness as a function of age and pharmacologically stimulated accommodation in rhesus monkeys. Exp Eye Res 86:746–752. https://doi.org/10.1016/j.exer.2008.01.022
Xu L, Cao WF, Wang YX et al (2008) Anterior chamber depth and chamber angle and their associations with ocular and general parameters: the Beijing Eye Study. Am J Ophthalmol 145:929–936. https://doi.org/10.1016/j.ajo.2008.01.004
Fontana ST, Brubaker RF (1980) Volume and depth of the anterior chamber in the normal aging human eye. Arch Ophthalmol 98:1803–1808
Ulvik SO, Seland JH, Wentzel-Larsen T (2005) Refraction, axial length and age-related maculopathy. Acta Ophthalmol Scand 83:419–423. https://doi.org/10.1111/j.1395-3907.2005.520_corr.x
Roy A, Kar M, Mandal D et al (2015) Variation of axial ocular dimensions with age, sex, height, BMI-and their relation to refractive status. J Clin Diagn Res 9:01–04. https://doi.org/10.7860/jcdr/2015/10555.5445
Maeng H-SRE, Chung T-Y, Chung E-S (2010) Effects of anterior chamber depth and axial length on refractive error after intraocular lens implantation. J Korean Ophthalmol Soc 51:195–202
Muller M, Dahmen G, Porksen E et al (2006) Anterior chamber angle measurement with optical coherence tomography: intraobserver and interobserver variability. J Cataract Refract Surg 32:1803–1808. https://doi.org/10.1016/j.jcrs.2006.07.014
Wu RY, Nongpiur ME, He MG et al (2011) Association of narrow angles with anterior chamber area and volume measured with anterior-segment optical coherence tomography. Arch Ophthalmol 129:569–574. https://doi.org/10.1001/archophthalmol.2011.68
Sorbara L, Maram J, Fonn D et al (2010) Metrics of the normal cornea: anterior segment imaging with the Visante OCT. Clin Exp Optom 93:150–156. https://doi.org/10.1111/j.1444-0938.2010.00472.x
Emre S, Doganay S, Yologlu S (2007) Evaluation of anterior segment parameters in keratoconic eyes measured with the Pentacam system. J Cataract Refract Surg 33:1708–1712. https://doi.org/10.1016/j.jcrs.2007.06.020
Oh YG, Minelli S, Spaeth GL et al (1994) The anterior chamber angle is different in different racial groups: a gonioscopic study. Eye (Lond) 8(Pt 1):104–108. https://doi.org/10.1038/eye.1994.20
Olsen T (2006) Prediction of the effective postoperative (intraocular lens) anterior chamber depth. J Cataract Refract Surg 32:419–424. https://doi.org/10.1016/j.jcrs.2005.12.139
Labiris G, Gkika M, Katsanos A et al (2009) Anterior chamber volume measurements with Visante optical coherence tomography and Pentacam: repeatability and level of agreement. Clin Exp Ophthalmol 37:772–774. https://doi.org/10.1111/j.1442-9071.2009.02132.x
Dinc U, Oncel B, Gorgun E et al (2009) Quantitative assessment of anterior chamber volume using slit-lamp OCT and Pentacam. Eur J Ophthalmol 19:411–415
Salouti R, Nowroozzadeh MH, Zamani M et al (2010) Comparison of anterior chamber depth measurements using Galilei, HR Pentacam, and Orbscan II. Optomet J Am Optomet Assoc 81:35–39. https://doi.org/10.1016/j.optm.2009.04.100
Auffarth GU, Tetz MR, Biazid Y et al (1997) Measuring anterior chamber depth with Orbscan Topography System. J Cataract Refract Surg 23:1351–1355
Lackner B, Schmidinger G, Skorpik C (2005) Validity and repeatability of anterior chamber depth measurements with Pentacam and Orbscan. Optom Vis Sci 82:858–861
Hashemi H, Khabazkhoob M, Miraftab M et al (2012) The distribution of axial length, anterior chamber depth, lens thickness, and vitreous chamber depth in an adult population of Shahroud, Iran. BMC Ophthalmol 12:50
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This project was supported by Deputy of Research of Shahid Beheshti University of Medical Sciences, the Iran.
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Hashemi, H., Yekta, A., Khodamoradi, F. et al. Anterior chamber indices in a population-based study using the Pentacam. Int Ophthalmol 39, 2033–2040 (2019). https://doi.org/10.1007/s10792-018-1037-5
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DOI: https://doi.org/10.1007/s10792-018-1037-5