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MP-3 measurement of retinal sensitivity in macular hole area and its predictive value on visual prognosis

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Abstract

Purpose

To explore a measuring method for retinal sensitivity in macular hole area by Microperimeter-3 (MP-3) and evaluate its predictive value on visual prognosis.

Methods

This was a case series study including 44 eyes of 44 patients with idiopathic macular hole. Retinal sensitivity inside and 0.5 degree outside the macular hole margin was measured, and its mean value was defined as macular hole sensitivity (MHS). Best-corrected visual acuity (BCVA), minimum diameter of macular hole (MD), IS/OS defect diameter, retinal sensitivity in 8 degrees and 2 degrees were also recorded preoperatively and 4 months after operation.

Results

All macular holes were closed after surgery. BCVA was significantly improved from 1.06 ± 0.39 at baseline to 0.31 ± 0.24 at 4 months postoperatively (P < 0.001). Meanwhile, MHS was also significantly improved from 12.02 ± 3.74 dB at baseline to 20.72 ± 4.00 dB at 4 months postoperatively (P < 0.001). MD, preoperative IS/OS defect diameter, preoperative BCVA, preoperative retinal sensitivity in 8 degrees and 2 degrees, and preoperative MHS were all correlated with postoperative BCVA at 4 months, but only preoperative MHS showed liner relationships to postoperative BCVA at 4 months by multivariate stepwise linear analysis.

Conclusions

Macular hole sensitivity by MP-3 could reflect the change of central retinal function after successful macular hole surgery. Compared to preoperative retinal sensitivity in 8 degrees and 2 degrees, preoperative macular hole sensitivity is a better predictor for visual prognosis.

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Authors and Affiliations

  1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No.1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, China

    Zengyi Wang, Yue Qi, Xida Liang, Yanping Yu, Jinqiu Chen, Jing Wang, Xinxin Liu & Wu Liu

  2. Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, China

    Zengyi Wang, Yue Qi, Xida Liang, Yanping Yu, Jinqiu Chen, Jing Wang, Xinxin Liu & Wu Liu

  3. Department of Ophthalmology, Kailuan General Hospital, Hebei United University, Tangshan, China

    Xinxin Liu

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  1. Zengyi Wang
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  2. Yue Qi
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  3. Xida Liang
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  4. Yanping Yu
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  6. Jing Wang
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Correspondence to Wu Liu.

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Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Cite this article

Wang, Z., Qi, Y., Liang, X. et al. MP-3 measurement of retinal sensitivity in macular hole area and its predictive value on visual prognosis. Int Ophthalmol 39, 1987–1994 (2019). https://doi.org/10.1007/s10792-018-1032-x

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  • DOI: https://doi.org/10.1007/s10792-018-1032-x

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