International Ophthalmology

, Volume 39, Issue 9, pp 2137–2142 | Cite as

Multimodal imaging of multifocal chorioretinitis secondary to endogenous candida infection

  • Chiara VeroneseEmail author
  • Chiara Maiolo
  • Annalisa Gurreri
  • Mariachiara Morara
  • Antonio P. Ciardella
  • Lawrence A. Yannuzzi
Photo Essay



To present multimodal imaging of multifocal chorioretinitis secondary to endogenous candida infection in a young adult.


A 49-year-old woman who presented for evaluation of bilateral endogenous candida chorioretinitis underwent complete ophthalmic examination, in addition to fundus photography (FP), enhanced depth imaging optical coherence tomography, fundus autofluorescence (FAF), fluorescein angiography (FA), indocyanine green angiography (ICGA) and optical coherence tomography angiography (OCTA).


Multimodal imaging of both eyes of the patient affected by endogenous candida chorioretinitis was performed. FP showed multiple white chorioretinal lesions at the posterior pole, FAF showed dark dot at the posterior pole surrounded by hyperautofluorescence area, FA showed early hyperfluorescence round perifoveal lesion at the posterior pole and small hyperfluorescence dots under the inferior retinal vessels. Early ICGA showed hypofluorescence dots at the posterior pole. Late ICGA showed dark hypofluorescence dots at the posterior pole surrounded by faint hyperautofluorescent ring. OCTA showed dark areas corresponded to hypoperfusion areas seen with early ICGA.


We reported multimodal imaging of an unusual occurrence of multifocal chorioretinitis due to immunosuppression. These findings suggested that the infection resulted from choroidal infiltration via the short posterior ciliary arteries with resultant breakthrough into the retina, rather than via the central retinal artery. By comparing findings on OCTA with data obtained from traditional systems, we are gaining essential information on the pathogenesis of endogenous candida chorioretinitis.


Bilateral endogenous candida chorioretinitis Multimodal imaging OCTA 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interests.


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Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  • Chiara Veronese
    • 1
    Email author
  • Chiara Maiolo
    • 2
  • Annalisa Gurreri
    • 2
  • Mariachiara Morara
    • 1
  • Antonio P. Ciardella
    • 1
  • Lawrence A. Yannuzzi
    • 3
    • 4
  1. 1.Ophthalmology Unit, S. Orsola-Malpighi HospitalUniversity of BolognaBolognaItaly
  2. 2.University of BolognaBolognaItaly
  3. 3.Vitreous Retina Macula Consultants of New YorkNew YorkUSA
  4. 4.LuEsther T. Mertz Retinal Research CenterManhattan, Eye, Ear and Throat HospitalNew YorkUSA

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