Inter- and intraobserver repeatability and reproducibility of choroidal thickness measurements using two different methods
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To measure the inter- and intraobserver repeatability and reproducibility of choroidal thickness measurements taken by the enhanced depth imaging of spectral-domain optical coherence tomography (EDI-OCT) in randomly selected subjects using two different protocols.
Twenty subjects of the Thessaloniki Eye Study database were randomly selected. The participants underwent EDI-OCT, and the choroidal thickness was measured on EDI images using two different protocols. All images were assessed by two examiners independently in two sessions in different days.
The interobserver intraclass correlation coefficient (ICC) for average choroidal thickness was 0.944. The average ICC for central, Cmin, and Cmax choroidal thickness was 0.899, 0.863, and 0.955, respectively. The interobserver ICC for average choroidal volume was 0.932. Intraobserver repeatability ICC for grader 1 ranged between 0.925 and 0.9720 and for grader 2 between 0.913 and 0.994.
Choroidal thickness measurements by EDI-OCT showed a high inter- and intraobserver reproducibility.
KeywordsChoroidal thickness EDI Repeatability
We would like to thank the ophthalmic technicians of the LaRCAO, 1st Department of Ophthalmology, Aristotle University of Thessaloniki, AHEPA Hospital, Irini Lachoura, Evgenia Zamba, Evmorfia Amiridou, Grigoria Tzoanou and Anastasia Rapti for their work and professionalism that greatly assisted the research. We are also grateful to Fei Yu from the Department of Biostatistics, UCLA, who provided advice that greatly assisted the research.
Compliance with ethical standards
Conflict of interest
All authors declare that they have no conflict of interest.
All procedures performed were in accordance with the ethical standards of the institutional research committee and with the 1964 Declaration of Helsinki comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
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