Case series of coexistence of polypoidal choroidal vasculopathy with other rare fundus diseases

  • Chengguo Zuo
  • Xiongze Zhang
  • Miaoling Li
  • Yuting Peng
  • Lan Mi
  • Bing Liu
  • Feng Wen
Original Paper



To record the coexistence of polypoidal choroidal vasculopathy (PCV) with other rare fundus diseases in a Chinese population.


In this retrospective hospital-based study, a chart review of 861 patients with newly diagnosed PCV was performed. The clinical features of rare fundus comorbidities of PCV were recorded.


Five eyes of 5 patients aged 63.4 ± 11.22 years (0.58%) had PCV coexisting with other fundus diseases in the same eye. Of the 5 PCV patients, 2 (0.23%) had myelinated nerve fiber, 2 (0.23%) had branch retinal vein occlusion, and 1 (0.12%) had retinal angiomatous proliferation.


We reported rare fundus comorbidities of PCV in a large Chinese cohort. These comorbidities included myelinated nerve fiber, branch retinal vein occlusion and retinal angiomatous proliferation. The combination might constitute an accidental occurrence.


Polypoidal choroidal vasculopathy Myelinated nerve fiber Branch retinal vein occlusion Retinal angiomatous proliferation 



This study was supported by the National Natural Science Foundation of China (Grant Numbers: 81400426, 81470647) and the Fundamental Research Funds for the Central Universities (the Young Teacher Training Project of Sun Yat-sen University, Grant Number: 15ykpy31).

Compliance with ethical standards

Conflicts of interest

The authors declare that there are no conflicts of interest regarding the publication of this paper.

Ethical approval

All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional ethics committee and with the 1964 Declaration of Helsinki and its later amendments.


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© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  1. 1.State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhouChina

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