Skip to main content

Advertisement

SpringerLink
Log in

Prediction of pupil size under binocular open-view settings using the new CASIA2 device

  • Original Paper
  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

Pupillometry should be performed under conditions as close to natural viewing as possible. The present study aimed to determine whether pupil size in binocular open-view settings can be predicted based on pupil size measured using the CASIA2 device.

Methods

The present study included 61 participants (25 men and 36 women; mean age, 49 ± 15 years; age range, 22–69 years) with no history of ophthalmic disease other than refractive errors and cataract. We measured pupil size using the new CASIA2 device and a binocular open-view digital pupillometer (FP-10000II, TMI Co., Ltd., Saitama). Intra-class and inter-class reliabilities were evaluated by measuring pupil times three times with each device (two independent examiners) in 21 of the 61 participants. Reproducibility was analyzed using intra-class and inter-class correlation coefficients (ICCs). Regression formulae for calculating FP10000II pupil size based on CASIA2 pupil size were developed via simple linear regression analyses.

Results

Both devices exhibited high ICC values (> 0.80). The regression formulae for calculating the FP10000II pupil size for the distant and near views based on CASIA2 pupil size were y = 0.5702x + 0.4611 (determination coefficient, 0.67) and y = 0.502x + 0.445 (determination coefficient, 0.64), respectively.

Conclusions

Pupil size under binocular open-view settings can be predicted based on simultaneous measurement of pupil size during evaluation of the anterior segment using the CASIA2 device. The calculated pupil size may represent a useful index for determining the most appropriate treatment strategy in candidates for cataract and refractive surgery.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Kawamorita T, Uozato H, Handa T, Ito M, Shimizu K (2010) Effect of pupil size on visual acuity in a laboratory model of pseudophakic monovision. J Refract Surg 26:378–380

    Article  PubMed  Google Scholar 

  2. Shimizu K (2011) Monovision strategies. CRST Europe, p 50–51. https://crstodayeurope.com/articles/2011-mar/monovision-strategies/

  3. Hayashi K, Hayashi H, Nakao F, Hayashi F (2001) Correlation between pupillary size and intraocular lens decentration and visual acuity of a zonal-progressive multifocal lens and a monofocal lens. Ophthalmology 108:2011–2017

    Article  CAS  PubMed  Google Scholar 

  4. Alio JL, Plaza-Puche AB, Férnandez-Buenaga R, Pikkel J, Maldonado M (2017) Multifocal intraocular lenses: an overview. Surv Ophthalmol 62:611–634

    Article  PubMed  Google Scholar 

  5. McDonald JE 2nd, El-Moatassem Kotb AM, Decker BB (2001) Effect of brimonidine tartrate ophthalmic solution 0.2% on pupil size in normal eyes under different luminance conditions. J Cataract Refract Surg 27:560–564

    Article  PubMed  Google Scholar 

  6. Lee JH, You YS, Choe CM, Lee ES (2008) Efficacy of brimonidine tartrate 0.2% ophthalmic solution in reducing halos after laser in situ keratomileusis. J Cataract Refract Surg 34:963–967

    Article  PubMed  Google Scholar 

  7. Chaidaroon W, Juwattanasomran W (2002) Colvard pupillometer measurement of scotopic pupil diameter in emmetropes and myopes. Jpn J Ophthalmol 46:640–644

    Article  PubMed  Google Scholar 

  8. Witting MD, Goyal D (2003) Normal pupillary size in fluorescent and bright light. Ann Emerg Med 41:247–250

    Article  PubMed  Google Scholar 

  9. Malyugin BE, Shpak AA, Pokrovskiy DF (2015) Posterior chamber phakic intraocular lens sizing based on iris pigment layer measurements by anterior segment optical coherence tomography. J Cataract Refract Surg 41:1616–1622

    Article  PubMed  Google Scholar 

  10. Goto S, Maeda N, Koh S, Ohnuma K, Hayashi K, Iehisa I, Noda T, Nishida K (2016) Prediction of postoperative intraocular lens position with angle-to-angle depth using anterior segment optical coherence tomography. Ophthalmology 123:2474–2480

    Article  PubMed  Google Scholar 

  11. Lucisano A, Ferrise M, Balestrieri M, Busin M, Scorcia V (2017) Evaluation of postoperative toric intraocular lens alignment with anterior segment optical coherence tomography. J Cataract Refract Surg 43:1007–1009

    Article  PubMed  Google Scholar 

  12. Shoji T, Kato N, Ishikawa S, Ibuki H, Yamada N, Kimura I, Shinoda K (2017) In vivo crystalline lens measurements with novel swept-source optical coherent tomography: an investigation on variability of measurement. BMJ Open Ophthalmol 1:e000058

    Article  PubMed  PubMed Central  Google Scholar 

  13. Wolffsohn JS, Hunt OA, Gilmartin B (2002) Continuous measurement of accommodation in human factor applications. Ophthalmic Physiol Opt 22:380–384

    Article  CAS  PubMed  Google Scholar 

  14. Kurz S, Krummenauer F, Pfeiffer N, Dick HB (2004) Monocular versus binocular pupillometry. J Cataract Refract Surg 30:2551–2556

    Article  PubMed  Google Scholar 

  15. Kobashi H, Kamiya K, Handa T, Ando W, Kawamorita T, Igarashi A, Shimizu K (2015) Comparison of subjective refraction under binocular and monocular conditions in myopic subjects. Sci Rep 5:12606

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Handa T, Shoji N, Kawamorita T, Shimizu K, Kawamura R, Shimizu N (2012) Development of a wide-field, binocular, open-view type electronic pupillometer. J Refract Surg 28:672–673

    PubMed  Google Scholar 

  17. Kanellopoulos AJ, Asimellis G, Georgiadou S (2015) Digital pupillometry and centroid shift changes after cataract surgery. J Cataract Refract Surg 41:408–414

    Article  PubMed  Google Scholar 

  18. Bilak S, Simsek A, Capkin M, Guler M, Bilgin B (2015) Biometric and intraocular pressure change after cataract surgery. Optom Vis Sci 92:464–470

    Article  PubMed  Google Scholar 

  19. Kamiya K, Shimizu K, Igarashi A, Ishikawa H (2010) Evaluation of pupil diameter after posterior chamber phakic intraocular lens implantation. Eye (Lond) 24:588–594

    Article  CAS  Google Scholar 

  20. Li D, Yang Y, Su C, Yin H, Liu X (2015) Pupil diameter changes in high myopes after collamer lens implantation. Optom Vis Sci 92:1161–1169

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Orthoptics and Visual Sciences, School of Health Sciences, International University of Health and Welfare, 2600-1, Kitakanemaru, Ohtawara, Tochigi, 324-8501, Japan

    Tsukasa Satou, Misae Ito & Takahiro Niida

  2. Eye Center, Sanno Hospital, Tokyo, Japan

    Tsukasa Satou, Sayaka Kato, Akihito Igarashi, Misae Ito, Shuntaro Tsunehiro, Manabu Koshimizu & Kimiya Shimizu

  3. International University of Health and Welfare, Tochigi, Japan

    Tsukasa Satou, Akihito Igarashi, Misae Ito, Shuntaro Tsunehiro, Manabu Koshimizu, Takahiro Niida & Kimiya Shimizu

Authors
  1. Tsukasa Satou
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sayaka Kato
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Akihito Igarashi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Misae Ito
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Shuntaro Tsunehiro
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Manabu Koshimizu
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Takahiro Niida
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Kimiya Shimizu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Tsukasa Satou.

Ethics declarations

Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements) or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Satou, T., Kato, S., Igarashi, A. et al. Prediction of pupil size under binocular open-view settings using the new CASIA2 device. Int Ophthalmol 39, 791–796 (2019). https://doi.org/10.1007/s10792-018-0879-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10792-018-0879-1

Keywords

Search

Navigation