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Mirror image of familial exudative vitreoretinopathy in identical twins

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Abstract

Purpose

To report the identical twins who had mirror fundus and angiographic images of familial exudative vitreoretinopathy (FEVR).

Case presentation

A pair of 16 year old female twins presented with mirror-image asymmetry of monocular decreased vision. The twins were born full term with normal weights. Neither twin revealed any medical disorders during childhood and there was no known family history of ocular disorders. On ocular examination, the best corrected visual acuity (BCVA) was 20/20 in OD and 20/63 in OS for twin 1. For the twin 2, the BCVAs were 20/63 and 20/20 for OD and OS, respectively. Intraocular pressures were within normal limits and anterior segment examinations were unremarkable for both twins. Dilated fundus examinations and angiographic images revealed characteristics FEVR appearance with mirror image phenomenon in the twins.

Conclusion

This is the first report describing identical twins with mirror images of FEVR. This report may confirm a strong underlying genetic inheritance in the pathogenesis of FEVR.

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Author information

Authors and Affiliations

  1. Department of Retinal Diseases, Ankara Ulucanlar Eye Training and Research Hospital, 06240, Ankara, Turkey

    Mehmet Yasin Teke

  2. Ophthalmology Department, Kars State Hospital, Kars, Turkey

    Kemal Tekin

  3. Ankara Ulucanlar Eye Training and Research Hospital, Ankara, Turkey

    Emre Aydemir & Fuat Yavrum

Authors
  1. Mehmet Yasin Teke
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  2. Kemal Tekin
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  3. Emre Aydemir
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  4. Fuat Yavrum
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Corresponding author

Correspondence to Mehmet Yasin Teke.

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Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this paper.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

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Informed consent was obtained from all participants included in the paper.

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Teke, M.Y., Tekin, K., Aydemir, E. et al. Mirror image of familial exudative vitreoretinopathy in identical twins. Int Ophthalmol 39, 935–941 (2019). https://doi.org/10.1007/s10792-018-0875-5

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  • DOI: https://doi.org/10.1007/s10792-018-0875-5

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