Multi-viral canaliculitis: case report and review of literature

  • Mohammad Javed Ali
  • Joveeta Joseph
  • Shweta Gupta
  • Sai Jeevana Madhuri Guda
Case Report



To report an atypical case of multiple viruses causing canaliculitis.


Case report of a young female presenting with atypical course of refractory unilateral canaliculitis with complete mid-bicanalicular obstructions. Canalicular scrapings were subjected to immunofluorescence techniques and polymerase chain reactions to identify the viruses.


Investigations revealed a canaliculitis of multi-viral etiology; herpes simplex virus and varicella zoster virus. A canalicular curettage followed by topical acyclovir helped in the resolution of canaliculitis.


An encounter with an atypical canaliculitis with negative bacteriology work up, suboptimal response to routine therapies, and mid-canalicular obstructions should alert the physician to investigate for viral etiology.


Viral Herpes simplex VZV Canaliculitis 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.


Dr. Ali receives royalties from Springer for his textbook “Principles and Practice of Lacrimal Surgery” and also for his treatise ‘Atlas of Lacrimal Drainage Disorders’. Other authors have none.

Patient consent

The patient/next of kin/guardian has consented to the submission of the case report for submission to the journal.


  1. 1.
    Bouzas AG (1973) Virus etiology of certain cases of lacrimal obstruction. Br J Ophthalmol 57:849–851CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Bouzas A (1965) Canalicular inflammation in ophthalmic cases of herpes zoster and herpes simplex. Am J Ophthalmol 60:713–716CrossRefPubMedGoogle Scholar
  3. 3.
    Sanford-Smith JH (1970) Herpes simplex canalicular obstruction. Br J Ophthalmol 54:456–460CrossRefGoogle Scholar
  4. 4.
    Coster DJ, Welham RAN (1979) Herpetic canalicular obstruction. Br J Ophthalmol 63:259–262CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    De Koning EWJ, van Bijsterveld OP (1983) Herpes simplex virus canaliculitis. Ophthalmologica 186:173–176CrossRefPubMedGoogle Scholar
  6. 6.
    Harris GJ, Hyndiuk RA, Fox MJ et al (1981) Herpetic canalicular obstruction. Arch Ophthalmol 99:282–283CrossRefPubMedGoogle Scholar
  7. 7.
    Keith CG (1968) Intubation of the lacrimal passages. Am J Ophthalmol 65:70–74CrossRefPubMedGoogle Scholar
  8. 8.
    McLean CJ, Rose GE (2000) Post-herpetic lacrimal obstruction. Ophthalmology 107:496–499CrossRefPubMedGoogle Scholar
  9. 9.
    Jager GV, van Bijsterveld OP (1997) Canalicular stenosis in the course of primary herpes simplex infection. Br J Ophthalmol 81:332CrossRefPubMedGoogle Scholar
  10. 10.
    Harley RD, Stefanyszyn MA, Apt L, Nelson LB (1987) Herpectic canalicular obstruction. Br J Ophthalmol 18:367–370Google Scholar
  11. 11.
    Sanke RF, Welham RA (1982) Lacrimal canalicular obstruction following chickenpox. Br J Ophthalmol 66:71–74CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  • Mohammad Javed Ali
    • 1
  • Joveeta Joseph
    • 2
  • Shweta Gupta
    • 1
  • Sai Jeevana Madhuri Guda
    • 2
  1. 1.Govindram Seksaria Institute of DacryologyL.V. Prasad Eye InstituteHyderabadIndia
  2. 2.Jhaveri Microbiology LaboratoryL. V. Prasad Eye InstituteHyderabadIndia

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