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Ocular biometric changes with different accommodative stimuli using swept-source optical coherence tomography

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Abstract

Purpose

To evaluate ocular biometric changes with different accommodative stimuli using a new swept-source optical biometer.

Methods

Only the right eye was analyzed. Each subject was measured six times with the IOLMaster 700 swept-source optical biometer (Carl Zeiss Meditec, Jena, Germany) with the subject looking at the stimulus shown by the instrument and with the subject looking at a target placed outside the instrument at 0D of vergence. Axial length (AL), anterior chamber depth (ACD), central corneal thickness (CCT), lens thickness (LT), white-to-white (WTW), and keratometry readings (K1 and K2) were evaluated in both cases. To assess if the changes found may affect the intraocular (IOL) power calculation for surgical applications, we have applied some formulae, using the software provided by the optical biometer manufacturer, to the ocular parameters found in both situations for three different types of IOLs.

Results

No statistically significant differences were found for AL, CCT, WTW, K1 and K2 between the subject looking at the stimulus of the biometer and looking at the outside target at 0D of vergence (p > 0.05). However, the measurement of ACD revealed a statistically significant reduction of 20 microns (p = 0.03) and, on the contrary, LT increased significantly 30 microns (p = 0.02). ACD and LT changes were highly correlated (R2 = 0.91). As for the IOL power calculation, in all cases, the mean change was lower than 0.25 D both for IOL power selection and residual refraction.

Conclusions

Although ACD and LT change significantly with different accommodative stimuli measured by swept-source optical biometry, these changes are not clinically relevant.

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Funding

Authors acknowledge financial support from the Spanish Government Grant Explora (SAF2013-49284-EXP) and a “Formación de Profesorado Universitario” Grant (FPU13/05332, Ministerio de Educación, Cultura y Deporte) awarded to Daniel Monsálvez-Romín.

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Authors and Affiliations

  1. Department of Optics and Optometry and Vision Sciences, University of Valencia, C/Dr. Moliner, 50, 46100, Burjassot, Spain

    Teresa Ferrer-Blasco, José J. Esteve-Taboada, Daniel Monsálvez-Romín & Robert Montés-Micó

  2. Department of Astronomy and Astrophysics, University of Valencia, C/Dr. Moliner, 50, 46100, Burjassot, Spain

    Miguel A. Aloy, José E. Adsuara & Pablo Cerdá-Durán

Authors
  1. Teresa Ferrer-Blasco
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  2. José J. Esteve-Taboada
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  3. Daniel Monsálvez-Romín
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  4. Miguel A. Aloy
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  5. José E. Adsuara
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  6. Pablo Cerdá-Durán
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  7. Robert Montés-Micó
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Corresponding author

Correspondence to José J. Esteve-Taboada.

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Conflict of interest

The authors declare no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Ferrer-Blasco, T., Esteve-Taboada, J.J., Monsálvez-Romín, D. et al. Ocular biometric changes with different accommodative stimuli using swept-source optical coherence tomography. Int Ophthalmol 39, 303–310 (2019). https://doi.org/10.1007/s10792-017-0813-y

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  • DOI: https://doi.org/10.1007/s10792-017-0813-y

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