International Ophthalmology

, Volume 35, Issue 4, pp 599–602 | Cite as

Multidrug-resistant Pseudomonas aeruginosa endophthalmitis in a silicone oil-filled eye treated with piperacillin/tazobactam: report of a case and review of literature

  • Neha Goel
  • Vishaal Bhambhwani
  • Basudeb Ghosh
Case Report


The incidence of endophthalmitis after pars plana vitrectomy is low. Silicone oil is a tamponading agent which has anti-microbial activity. Post-operative endophthalmitis following vitrectomy with silicone oil tamponade has been rarely reported. We describe the case of a young male who underwent pars plana vitrectomy with silicone oil for retinal detachment with a giant retinal tear. He developed a clinical picture suggestive of endophthalmitis on the first post-operative day, and vitreous culture grew multidrug-resistant Pseudomonas aeruginosa. He was treated with intravitreal piperacillin/tazobactam, along with appropriate surgical management. This was followed by resolution of the infection with a remarkable improvement in visual acuity. This is the first case of multidrug-resistant Pseudomonas aeruginosa endophthalmitis following pars plana vitrectomy with silicone oil treated successfully with piperacillin/tazobactam.


Post-vitrectomy endophthalmitis Silicone oil Pseudomonas aeruginosa Piperacillin/tazobactam 


Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  1. 1.ICARE Eye Hospital and Postgraduate InstituteNoidaIndia
  2. 2.New DelhiIndia
  3. 3.Guru Nanak Eye CentreMaulana Azad Medical CollegeNew DelhiIndia

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