International Ophthalmology

, Volume 35, Issue 2, pp 261–268 | Cite as

Hemodynamics of focal choroidal excavations

Case Report


The purpose of this study was to investigate the hemodynamics of focal choroidal excavations (FCEs). Four eyes of four patients with a FCE were studied. Indocyanine green angiography (ICGA), laser speckle flowgraphy (LSFG), optical coherence tomography (OCT), and multi-focal electroretinography (mfERG) were performed to investigate the choroidal hemodynamics and the morphological and functional changes. The mean depth of the FCE determined by OCT was 222.5 ± 49.5 μm with a range of 164–272 μm. In one case, subretinal fluid was observed in the excavation, and in three cases, subretinal fluid was not observed. ICGA showed hypofluorescence, and laser flowgraphy (LSFG) showed decreased choroidal blood flow at the excavation in all cases. Three cases were symptomatic, and the amplitudes of the mfERGs were reduced. FCEs cause a decrease of choroidal blood flow. In three of four cases, the mfERGs were depressed over the FCEs leading to symptoms.


Focal choroidal excavation LSFG ICG Hemodynamics OCT MBR 



Supported in part by research grant 22390322 and 23659808 from the Japan Society for the Promotion of Science, Tokyo, Japan.


  1. 1.
    Jampol L, Shankle J, Schroeder R, Tornambe P, Spade RF, Hee MR (2006) Diagnostic and therapeutic challenges. Retina 26:1072–1076CrossRefPubMedGoogle Scholar
  2. 2.
    Margolis R, Mukkamala SK, Jampol LM et al (2011) The expanded spectrum of focal choroidal excavation. Arch Ophthalmol 129(10):1320–1325CrossRefPubMedGoogle Scholar
  3. 3.
    Isono H, Kishi S, Kimura Y, Hagiwara N, Konishi N, Fujii H (2003) Observation of choroidal circulation using index of erythrocytic velocity. Arch Ophthalmol 121:225–231CrossRefPubMedGoogle Scholar
  4. 4.
    Konishi N, Tokimoto Y, Kohra K et al (2002) New laser speckle flowgraphy using CCD camera. Opt Rev 9:163–169CrossRefGoogle Scholar
  5. 5.
    Obata R, Takahashi H, Ueta T, Yuda K, Kume K, Yanagi Y (2013) Tomographic and angiographic characteristics of eyes with macular focal choroidal excavation. Retina 33:1201–1210CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  1. 1.Department of Ophthalmology and Visual ScienceTokyo Medical and Dental UniversityBunkyo-KuJapan

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