International Ophthalmology

, Volume 35, Issue 5, pp 663–671 | Cite as

The spectrum of presumed tubercular uveitis in Tunisia, North Africa

  • Sana Khochtali
  • Salma Gargouri
  • Nesrine Abroug
  • Imen Ksiaa
  • Sonia Attia
  • Dorra Sellami
  • Jamel Feki
  • Moncef Khairallah
Original Paper


The purpose of this study was to analyze the spectrum of presumed tubercular uveitis in Tunisia, North Africa. We retrospectively reviewed the clinical records of 38 patients (65 eyes) diagnosed with presumed tubercular uveitis at two referral centers in Tunisia, between January 2009 and December 2011. Mean age at presentation was 42.7 years. Twenty-four patients were women (63.2 %) and 14 (36.8 %) were men. Twenty-three eyes (35.4 %) had posterior uveitis, 21 eyes (32.3 %) had intermediate uveitis, 13 eyes (20 %) had panuveitis, and 8 eyes (12.3 %) had anterior uveitis. Ocular findings included vitritis in 67.7 % of eyes, posterior synechiae in 47.7 %, multifocal non-serpiginoid choroiditis in 23.1 %, multifocal serpiginoid choroiditis in 21.5 %, periphlebitis in 21.5 %, and mutton-fat keratic precipitates in 20 %. Anti-tubercular treatment was prescribed in 33 patients (86.8 %) and was associated with systemic corticosteroids in 20 patients (52.6 %) and periocular injections of corticosteroids in four patients (10.5 %). After a mean follow-up of 14.2 months (range, 10–58), inflammation was controlled, with a significant improvement in visual acuity (VA) (p = 0.028). However, recurrences developed in two patients (5.3 %). Final VA was better than 20/40 in 27 eyes (41.5 %) and less than 20/200 in five eyes (7.7 %). In Tunisia, all anatomic types are possible in tuberculosis-associated uveitis, but posterior and intermediate uveitis are more frequent. Vitritis, posterior synechiae, multifocal serpiginoid or non-serpiginoid choroiditis, and periphlebitis are the most common manifestations.


Uveitis Posterior uveitis Retinal vasculitis Tuberculosis Tuberculin skin test Interferon-gamma release tests 



This work has been supported by the Ministry of Higher Education and Research of Tunisia.


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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Sana Khochtali
    • 1
  • Salma Gargouri
    • 2
  • Nesrine Abroug
    • 1
  • Imen Ksiaa
    • 1
  • Sonia Attia
    • 1
  • Dorra Sellami
    • 2
  • Jamel Feki
    • 2
  • Moncef Khairallah
    • 1
  1. 1.Department of OphthalmologyFattouma Bourguiba University Hospital, Faculty of Medicine, University of MonastirMonastirTunisia
  2. 2.Department of OphthalmologyHabib Bourguiba University Hospital, Faculty of Medicine, University of SfaxSfaxTunisia

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