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International Ophthalmology

, Volume 33, Issue 2, pp 117–123 | Cite as

Microbial keratitis following vegetative matter injury

  • Mukesh Taneja
  • Jatin N. Ashar
  • Anurag Mathur
  • Suma Nalamada
  • Prashant Garg
Original Paper

Abstract

The purpose of the present study was to analyze the microbiological profile of cases of keratitis following trauma with vegetative matter in a tertiary care center. A retrospective review of the medical records of 49 patients with keratitis following vegetative matter injury over a 3-month period was performed. All patients underwent corneal scraping for smears and inoculation onto various culture media. The microbiological profile was based on the smear and culture reports. For patients who were culture-negative, outcome after standard empirical antibacterial therapy as per hospital protocol was analyzed. Thirteen patients with corneal ulcers had fungal etiology, eight had bacterial etiology, and two had protozoal etiology, while 13 patients were polymicrobial and 13 were culture-negative. Polymicrobial infections were mainly bacterial (eight cases), and the remaining five cases had coexistent fungal and bacterial etiology. The treatment was directed to the specific organism and patients improved with medical or surgical therapy. Only a third of culture-negative cases showed fungal etiology on biopsy or histopathology after keratoplasty while a third showed improvement with therapy. Corneal infections following vegetative matter trauma show a varied etiological profile; however, bacterial and polymicrobial infections are more prevalent. Empirical anti-fungal therapy, as commonly practiced, must be avoided in cases with vegetative matter injury.

Keywords

Vegetative matter Trauma Infectious keratitis Fungal ulcer Antifungal agents Microbial keratitis Empirical therapy 

Notes

Acknowledgments

This study was supported by Hyderabad Eye Research Foundation, India.

Conflict of interest

The authors do not have any financial interest or any conflicting relationship in any of the issues or products referred to in the manuscript.

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Copyright information

© Springer Science+Business Media Dordrecht 2012

Authors and Affiliations

  • Mukesh Taneja
    • 1
  • Jatin N. Ashar
    • 2
    • 3
  • Anurag Mathur
    • 4
  • Suma Nalamada
    • 1
    • 5
  • Prashant Garg
    • 1
  1. 1.Cornea and Anterior Segment ServicesL.V. Prasad Eye InstituteHyderabadIndia
  2. 2.Bombay City Eye InstituteMumbaiIndia
  3. 3.Akshar Eye ClinicMaladIndia
  4. 4.Anand Eye HospitalJaipurIndia
  5. 5.Jhaveri Microbiology CenterHyderabad Eye Research Foundation, L.V. Prasad Eye InstituteHyderabadIndia

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