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International Ophthalmology

, Volume 30, Issue 6, pp 709–711 | Cite as

Early unilateral macular sensitivity changes in microperimetry in a case of pituitary adenoma

  • M. R. Romano
  • Martina Angi
  • Vito Romano
  • Joaquin Marticorena
  • Ferdinando Romano
Case Report
  • 61 Downloads

Abstract

The value of the MP-1 microperimeter in early diagnosis of pituitary tumours by detection of changes in macular sensitivity is described. A 21-year-old female presented with blurred vision in the right eye. Ophthalmic examination was unremarkable. Static perimetry of the central visual field (30°) was performed by use of a Humphrey automatic perimeter, and the retinal sensitivity of the 12 central degrees was measured by use of the MP-1. Static perimetry revealed a peripheral visual field defect without involvement of the macular region. The MP-1 revealed an important loss of sensitivity (3.4 ± 4.8 dB) in the central 12°. Magnetic resonance imaging revealed a pituitary adenoma with sellar and suprasellar extension. Three months after surgical removal, use of the MP-1 revealed complete recovery of the sensitivity (19.28 ± 2.5 dB), fixation location, and fixation stability of the right eye. In pituitary tumours, the presence of a sub-clinical form of macular involvement can be demonstrated and followed-up accurately by use of the MP-1.

Keywords

Macular sensitivity Microperimetry Pituitary adenoma Early diagnosis 

Notes

Acknowledgements

The authors indicate no financial support or financial conflict of interest. Involved in conception, design of the study, and data analysis (M.R.R.); involved in collection and management of the data (M.R.R., M.A., V.R., and J.M.); involved in the provision of patients (V.R. and F.R.); involved in the preparation of the manuscript (M.R.R. and V.R.); involved in the review and approval of the manuscript (M.R.R., M.A., and J.M.). None of the authors has a proprietary interest.

References

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    Gutowski NJ, Heron JR, Scase MO (1997) Early impairment of foveal magno- and parvocellular pathways in juxta chiasmal tumours. Vision Res 37:1401–1408CrossRefPubMedGoogle Scholar
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    Hirai T, Ito Y, Arai M et al (2002) Loss of stereopsis with optic chiasmal lesions and stereoscopic tests as a differential test. Ophthalmology 109:1692–1702CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • M. R. Romano
    • 1
  • Martina Angi
    • 1
  • Vito Romano
    • 2
  • Joaquin Marticorena
    • 1
  • Ferdinando Romano
    • 2
  1. 1.St. Paul’s Eye UnitRoyal Liverpool University HospitalLiverpoolUK
  2. 2.Department of OphthalmologyS. Sebstiano HospitalCasertaItaly

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