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Descemet’s stripping endothelial keratoplasty: is it an option for congenital hereditary endothelial dystrophy?

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Abstract

The purpose of this study was to report our experience of an attempted Descemet’s stripping automated endothelial keratoplasty (DSAEK) in a patient with congenital hereditary endothelial dystrophy (CHED). A 7-year-old boy presented with the complaints of decreased vision in his right eye. The left eye had undergone penetrating keratoplasty at the age of 5 years. He was diagnosed as a case of CHED, and a DSAEK was planned for him. Due to technical difficulties during Descemet’s membrane scoring and stripping and poor visualization, the procedure had to be abandoned and converted to a full thickness penetrating keratoplasty. To the best of our knowledge, this is the first reported case of an attempted DSAEK in a patient with CHED. Proper DSAEK case selection should include adequate visualization of the endothelium and anterior chamber. Severe stromal haze and edema may prevent necessary surgical observation during the procedure, and a full thickness penetrating keratoplasty may be required.

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References

  1. Graham MA, Azar NF, Dana MR (2001) Visual rehabilitation in children with congenital hereditary endothelial dystrophy. Int Ophthalmol Clin 4:9–18

    Article  Google Scholar 

  2. Dana MR, Moyes AL, Gomes JA et al (1995) The indications for and outcome in pediatric keratoplasty. A multicenter study. Ophthalmology 102:1129–1138

    CAS  PubMed  Google Scholar 

  3. Gorovoy MS (2006) Descemet stripping automated endothelial keratoplasty (DSAEK). Cornea 25:886–889

    Article  PubMed  Google Scholar 

  4. Price MO, Price FW (2007) Descemet’s stripping endothelial keratoplasty. Curr Opin Ophthalmol 18:290–294

    Article  PubMed  Google Scholar 

  5. Allan BD, Terry MA, Price FW et al (2007) Corneal transplant rejection rate and severity after endothelial keratoplasty. Cornea 26:1039–1042

    Article  PubMed  Google Scholar 

  6. Price MO, Price FW Jr (2007) Descemet’s stripping endothelial keratoplasty for treatment of iridocorneal endothelial syndrome. Cornea 26:493–497

    Article  PubMed  Google Scholar 

  7. Culbertson WW (2006) Descemet’s stripping endothelial keratoplasty. Int Ophthalmol Clin 46:155–168

    Article  PubMed  Google Scholar 

  8. Price FW Jr, Price MO (2005) Descemet’s stripping with endothelial keratoplasty in 50 eyes; a refractive neutral cornea transplant. J Refract Surg 21:339–345

    PubMed  Google Scholar 

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Acknowledgments

This research was financially supported by Aditya Jyot Research Foundation, Dadar, Mumbai, India.

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Authors and Affiliations

  1. Department of Cornea, Massachusetts Eye and Ear Infirmary, Boston, MA, USA

    Roberto Pineda II

  2. Department of Cornea and External Diseases, Aditya Jyot Eye Hospital, Plot No-153, Road No-9, Major Parmeshwaran Road, Wadala, Mumbai, 400031, India

    Vandana Jain

  3. Department of Ophthalmic and Facial Plastic Surgery, Orbital Diseases, and Ocular Oncology, Aditya Jyot Eye Hospital, Wadala, Mumbai, 400031, India

    Debraj Shome

  4. Department of Ocular Oncology, Tata Memorial Centre, Mumbai, India

    Debraj Shome

  5. Orbis Flying Eye Hospital, New York, NY, USA

    David C. Hunter

  6. Department of Retina, Aditya Jyot Eye Hospital, Mumbai, USA

    Sundaram Natarajan

Authors
  1. Roberto Pineda II
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  2. Vandana Jain
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  3. Debraj Shome
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  4. David C. Hunter
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  5. Sundaram Natarajan
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Corresponding author

Correspondence to Vandana Jain.

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Pineda, R., Jain, V., Shome, D. et al. Descemet’s stripping endothelial keratoplasty: is it an option for congenital hereditary endothelial dystrophy?. Int Ophthalmol 30, 307–310 (2010). https://doi.org/10.1007/s10792-009-9315-x

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  • DOI: https://doi.org/10.1007/s10792-009-9315-x

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