Abstract
The effect of growth conditions (supersaturation, relative concentrations of precursors, solution pH, and process duration) on the phase composition and structural properties of calcium phosphate coatings is studied. The results are used to determine the concentration boundary of metastable, supersaturated solutions at 37°C and a Ca/P molar ratio of 1.67 (hydroxyapatite stoichiometry). High supersaturations are shown to result in the growth of mixed-phase coatings: hydroxyapatite + octacalcium phosphate. At low supersaturations, single-phase hydroxyapatite coatings are obtained. The coatings consist of preferentially oriented nanocrystallites, independent of the growth conditions. The texture of the coatings and the size of the nanocrystallites are most sensitive to the growth duration.
Similar content being viewed by others
REFERENCES
Dorozhkin, S.V. and Epple, M., Die biologische und medizinische Bedeutung von Calciumphosphaten, Angew. Chem., 2002, vol. 114, no.17, pp. 48–55.
Nielsen, A.E., Electrolyte Crystal Growth Mechanisms, J. Cryst. Growth, 1984, vol. 67, no.2, pp. 289–310.
Campbell, A.A., Song, L., Li, X., et al., Development, Characterization, and Anti-Microbial Efficacy of Hydroxyapatite-Chlorhexidine Coatings Produced by Surface-Induced Mineralization, J. Biomed. Mater. Res., 2000, vol. 53, no.4, pp. 400–407.
Vosel’, S.V. and Purtov, P.A., Calculation of the Critical Supersaturation for Solation in a Dilute Binary Solution in the Explosive Nucleation Model, Zh. Fiz. Khim., 2004, vol. 78, no.3, pp. 536–542.
Ahn, E.S., Gleason, N.J., Nakahira, and Ying, J.Y., Nanostructure Processing of Hydroxyapatite-Based Bioceramics, Nano Lett., 2001, vol. 1, no.3, pp. 149–153.
Veresov, A.G., Controlled Synthesis of Hydroxyapatite-Based Fine-Particle Materials, Cand. Sci. (Chem.) Dissertation, Moscow: Mosk. Gos. Univ., 2003.
Li, F., Feng, Q.L., Cui, F.Z., et al., A Simple Biomimetic Method for Calcium Phosphate Coating, Surf. Coat. Technol., 2002, vol. 154, no.1, pp. 88–93.
Mao, Ch.V., Li, H., Ma, Ch., and Feng, Q., Oriented Growth of Phosphates on Polycrystalline Titanium in a Process Mimicking Biomineralization, J. Cryst. Growth, 1999, vol. 206, no.4, pp. 308–321.
Moreno, E.C. and Varughese, K.J., Crystal Growth of Apatites from Dilute Solutions, J. Cryst. Growth, 1981, vol. 53, no.1, pp. 20–30.
Abbona, F., Lundaer Madsen, H.E., and Boistelle, R., The Initial Phases of Calcium and Magnesium Phosphates Precipitated from Solutions of High to Medium Concentrations, J. Cryst. Growth, 1986, vol. 74, no.3, pp. 581–590.
Author information
Authors and Affiliations
Additional information
__________
Translated from Neorganicheskie Materialy, Vol. 41, No. 8, 2005, pp. 985–989.
Original Russian Text Copyright © 2005 by Savvin, Kryzhanovskaya, Tolmachev.
Rights and permissions
About this article
Cite this article
Savvin, Y.N., Kryzhanovskaya, A.S. & Tolmachev, A.V. Effect of Growth Conditions on the Structural Properties of Calcium Phosphate Coatings Prepared in the System CaCl2-KH2PO4-KOH-HCl-H2O. Inorg Mater 41, 864–868 (2005). https://doi.org/10.1007/s10789-005-0227-5
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s10789-005-0227-5