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International Journal of Thermophysics

, Volume 33, Issue 10–11, pp 1827–1833 | Cite as

Absorption Peaks: α, β, γ and Their Covariance with Age and Hemoglobin in Human Blood Samples Using Photoacoustic Spectroscopy

  • J. L. González-Domínguez
  • C. Hernández-Aguilar
  • F. A. Domínguez-Pacheco
  • E. Martínez-Ortiz
  • A. Cruz-Orea
  • F. Sánchez-Sinencio
Article

Abstract

This study reports the absorption peaks α, β, γ in the Soret band of photoacoustic (PA) signals and their covariance with age and hemoglobin in human blood samples through PA spectroscopy. Samples were taken randomly from a masculine population grouped in three categories according to age: infants, young adults, and senior adults. Samples were prepared with two drops of blood from a 0.5 mL insulin syringe with a needle gauge 31G over 5 mm circles of filter paper. It was observed that the PA signal, the amplitude as a function of the wavelength, has a behavior as that reported for human blood for the three absorption peaks α, β, γ. In particular, the ratio γ/ β is due to electronic transitions associated with charge-transfer interactions of iron orbitals with the ligand states. Through an evaluation of optical absorption peaks in blood samples and their covariance with age and hemoglobin concentration, a relationship was found for the ratio peaks γ/ β and γ/ α with such parameters. Specifically, a negative covariance in the Soret band of the ratio peaks γ/ β and γ/ α with respect to both age and hemoglobin was found. This showed a tendency in their behavior. Further experiments of different populations may corroborate these conclusions.

Keywords

Absorption peaks Human blood Photoacoustic spectroscopy Soret band 

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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • J. L. González-Domínguez
    • 1
  • C. Hernández-Aguilar
    • 1
  • F. A. Domínguez-Pacheco
    • 1
  • E. Martínez-Ortiz
    • 1
  • A. Cruz-Orea
    • 2
  • F. Sánchez-Sinencio
    • 2
  1. 1.Departamento de Sistemas de la Sección de Estudios de Posgrado e Investigación (SEPI), Escuela Superior de Ingeniería Mecánica y Eléctrica-Zacatenco (ESIME)Instituto Poitécnico Nacional (IPN) Unid. Prof., “Adolfo López Mateos,” Edif. 5MexicoMexico
  2. 2.Departamento de FísicaCINVESTAV–IPNMexicoMexico

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