Abstract
Nanoparticles appear to be ideally suited for applications in targeted thermal effects in medical therapies and photothermally activated drug delivery; all depend critically on the thermal transport between the nanoparticles and the surrounding liquid. In this work thermal lens spectroscopy (TLS) was used to determine the thermal diffusivity of protoporphyrin IX (PpIX) solutions mixed with gold metallic nanoparticles. PpIX disodium salt (DS) was used in a HCl solution at 25%. Fluids containing gold (Au) nanoparticles at different concentrations were prepared and added to the PpIX solutions. For each solution, UV–Vis spectroscopy was used to obtain the optical absorption spectrum, and transmission electron microscopy (TEM) was used to obtain the gold nanoparticle size. From the TLS signal intensity, it was possible to determine the characteristic time constant of the transient thermal by fitting the theoretical expression to the experimental data. From this characteristic time, the thermal diffusivity was obtained for each solution. The results show that the thermal diffusivity of PpIX mixed with gold nanoparticles increases with an increase of the nanoparticle metallic concentration.
Similar content being viewed by others
References
Hamad Schifferli K., Scwartz J.J., Santos A.T., Zhang S.G., Jacobson J.M. (2002) . Nature 415, 152
Loo C., Lin A., Hirsch L., Lee M.H., Barton J., Halas N., West J., Drezck R. (2004) . Technol. Cancer Res. Treat. 3, 33
O’Neal D.P., Hirsch L.R., Halas N.J., Payne J.D., J.L.West (2004). Cancer Lett. 209, 171
Huttmann G., Birngruber R. (1999). IEEE J. Sel. Top. Quant 5, 954
Link S., Furube A., Mohamed M.B., Asahi T., Masuhara H., El-Sayed M.A. (2002). J. Phys. Chem. B 106, 945
Bigot J.Y., Halte V., Merle J.C., Daunois A. (2000). Chem. Phys. 251, 181
Zhang J.Z. (1977). Acc. Chem. Res. 30, 432
Mohamed M.B., Ahmadi T.S., Link S., Braun M., El-Sayed M.A. (2001). Chem. Phys. Lett. 343, 55
Kennedy J.C., Pottier R.H., Pross D.C. (1990). J. Photochem. Photobiol. Biol. B. 6, 143
Shen J., Lowe R.D., Snook R.D. (1992). Chem. Phys. 165, 385
Shen J., Snook R.D. (1993). J. Appl. Phys. 73: 5286
Brown S.M., Baesso M.L., Shen J., Snook R.D. (1993). Anal. Chim. Acta. 282, 711
Park J., Privman V., Matijevic E. (2001). J. Phys. Chem. B. 105, 11630
Sánchez-Ramírez J.F., Jiménez-Pérez J.L., Carbajal-Valdez R., Cruz-Orea A., Gutierrez-Fuentes R., Herrera-Pérez J.L. (2006). Int. J. Thermophys. 27: 1181
Gouterman M., in In the Porphyrins, vol. III, Physical Chemistry, Part A, Chap. 1, ed. by Dolphin D. (Academic, London, 1978)
R.C. Weast (ed.), Handbook of Chemistry and Physics, 67th edn. (Chemical Rubber Co., Boca Raton, Florida, 1986–1987)
Mulvaney P. (1996). Langmuir 12, 788
Chandrasekharan N., Kamat P.V., Hu J., Jones G. (2000). II J. Phys. Chem. B 104, 11103
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Gutiérrez Fuentes, R., Sánchez Ramírez, J.F., Jiménez Pérez, J.L. et al. Thermal Diffusivity Determination of Protoporphyrin IX Solution Mixed with Gold Metallic Nanoparticles. Int J Thermophys 28, 1048–1055 (2007). https://doi.org/10.1007/s10765-007-0225-8
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10765-007-0225-8