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Blood Biochemical Reference Intervals for Free-Ranging Olive Baboons (Papio anubis) in Kenya

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Abstract

Biochemical reference intervals are important for assessing the health of target species and populations by identifying abnormalities in key blood parameters. Although reference intervals have been established for baboons in captivity, the lack of data from free-ranging individuals makes it difficult to interpret the results of their blood chemistry panels or to assess and monitor the health of wild baboon populations. The goal of this study was therefore to establish serum biochemical reference intervals for free-ranging olive baboons (Papio anubis) in Kenya. We evaluated 14 biochemical parameters from 28 baboons sampled at the Mpala Research Center, Nanyuki, Kenya. Reference intervals obtained from this wild population were comparable to those from captive baboon populations. Alkaline phosphatase (ALP) and phosphorus levels differed significantly among age classes; both were higher in subadult and juvenile baboons than in adults. However, none of the components of the blood biochemistry panel differed significantly between the sexes. The reference intervals we report provide a baseline for the evaluation and treatment of free-ranging olive baboons and provide context for interpreting the biochemical profiles of captive individuals.

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References

  • Brenner, D., Lewbart, G., Stebbins, M., & Herman, D. W. (2002). Health survey of wild and captive bog turtles (Clemmys Muhlenbergii) in North Carolina and Virginia. Journal of Zoo and Wildlife Medicine, 33(4), 311–316.

    Article  PubMed  Google Scholar 

  • Farine, D. R., Strandburg-Peshkin, A., Couzin, I. D., Berger-Wolf, T. Y., & Crofoot, M. C. (2017). Individual variation in local interaction rules can explain emergent patterns of spatial organization in wild baboons. Proceedings of the Royal Society of London B: Biological Sciences, 284, 20162243.

    Article  Google Scholar 

  • Fox, M., Brieva, C., Moreno, C., MacWilliams, P., & Thomas, C. (2008). Hematologic and serum biochemistry reference values in wild-caught white-footed tamarins (Saguinus leucopus) housed in captivity. Journal of Zoo and Wildlife Medicine, 39(4), 548–557.

    Article  PubMed  Google Scholar 

  • Foy, H., Kondi, A., & Mbaya, V. (1965). Hematologic and biochemical indices in the East African baboon. Blood, 26(5), 682–686.

    CAS  PubMed  Google Scholar 

  • Friedrichs, K. R., Harr, K. E., Freeman, K. P., Szladovits, B., Walton, R. M., et al (2012). ASVCP reference interval guidelines: Determination of de novo reference intervals in veterinary species and other related topics. Veterinary Clinical Pathology, 41(4), 441–453.

    Article  PubMed  Google Scholar 

  • García, I., Napp, S., Zorrilla, I., Vargas, A., Pastor, J., et al (2010). Determination of serum biochemical reference intervals for the Iberian lynx (Lynx pardinus). The Veterinary Journal, 183(2), 201–204.

    Article  CAS  PubMed  Google Scholar 

  • Geffré, A., Concordet, D., Braun, J. P., & Trumel, C. (2011). Reference value advisor: A new freeware set of macroinstructions to calculate reference intervals with Microsoft Excel. Veterinary Clinical Pathology, 40(1), 107–112.

    Article  PubMed  Google Scholar 

  • Gilbert, S. F., & Barresi, M. J. S. (2016). Developmental biology, 11th ed. Sunderland: Sinauer Associates.

    Google Scholar 

  • Harewood, W. J., Gillin, A., Hennessy, A., Armistead, J., Horvath, J. S., & Tiller, D. J. (1999). Biochemistry and haematology values for the baboon (Papio hamadryas): The effects of sex, growth, development and age. Journal of Medical Primatology, 28(1), 19–31.

    Article  CAS  PubMed  Google Scholar 

  • Havill, L., Snider, C., Leland, M., Hubbard, G., Theriot, S., & Mahaney, M. (2003). Hematology and blood biochemistry in infant baboons (Papio hamadryas). Journal of Medical Primatology, 32(3), 131–138.

    Article  CAS  PubMed  Google Scholar 

  • Junge, R. E., & Louis, E. E. (2005). Preliminary biomedical evaluation of wild ruffed lemurs (Varecia variegata and V. rubra). American Journal of Primatology, 66(1), 85–94.

    Article  PubMed  Google Scholar 

  • Kingdon, J., Butynski, T. M., & De Jong, Y. (2008). Papio anubis. IUCN Red List of Threatened Species.

  • Maas, M., Keet, D. F., & Nielen, M. (2013). Hematologic and serum chemistry reference intervals for free-ranging lions (Panthera leo). Research in Veterinary Science, 95(1), 266–268.

    Article  CAS  PubMed  Google Scholar 

  • Melton, C. (1982). Blood parameters of the wild chacma baboon, Papio ursinus. African Zoology, 17(2), 85–90.

    Article  Google Scholar 

  • Percin, F., & Konyalioglu, S. (2008). Serum biochemical profiles of captive and wild northern bluefin tuna (Thunnus thynnus L. 1758) in the Eastern Mediterranean. Aquaculture Research, 39(9), 945–953.

    Article  CAS  Google Scholar 

  • Ramer, J. C., MacWilliams, P., & Paul-Murphy, J. (1995). Effects of hemolysis and frozen storage on serum electrolyte and chemistry values in cotton-top tamarins (Saguinus oedipus). Journal of Zoo and Wildlife Medicine, 26, 61–66.

    Google Scholar 

  • Rangel-Mendoza, J., Weber, M., Zenteno-Ruiz, C. E., López-Luna, M. A., & Barba-Macías, E. (2009). Hematology and serum biochemistry comparison in wild and captive Central American river turtles (Dermatemys mawii) in Tabasco, Mexico. Research in Veterinary Science, 87(2), 313–318.

    Article  CAS  PubMed  Google Scholar 

  • Snider, C., Dick Jr., E., McGlasson, D., Robbins, M., Sholund, R., et al (2009). Evaluation of four hematology and a chemistry portable benchtop analyzers using non-human primate blood. Journal of Medical Primatology, 38(6), 390–396.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Strandburg-Peshkin, A., Farine, D. R., Couzin, I. D., & Crofoot, M. C. (2015). Shared decision-making drives collective movement in wild baboons. Science, 348(6241), 1358–1361.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Strandburg-Peshkin, A., Farine, D. R., Crofoot, M. C., & Couzin, I. D. (2017). Habitat and social factors shape individual decisions and emergent group structure during baboon collective movement. ELife, 6, e19505.

    Article  PubMed  PubMed Central  Google Scholar 

  • Teare, J. (2002). Physiological data reference values. Eagan: International Species Information System.

    Google Scholar 

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Acknowledgments

We thank Kenya National Science and Technology Council, the Kenyan Wildlife Service, and the Mpala Research Centre for permission to conduct this research (permit #: NCST/RCD/12B/012/26B). We thank M. Wikelski, E. Bermingham, D. Rubenstein and M. Kinnaird for logistical support, and R. Kays, R. Lessnau, S. Alavi, J. Nairobi, R. Nelson, H. Nelson, M. Ngila, J. Halkano, and J. Kiseme for help with animal capture. We acknowledge funding from the NSF (IOS-EAGER-1250895; III-1514174), the Max Planck Institute for Ornithology, the Smithsonian Tropical Research Institute, and Princeton University. Dr. Joanna Setchell and two anonymous reviewers provided helpful feedback and suggestions on a previous version of this manuscript. M. C. Crofoot and S. Murray conceived this study. M. Mutinda, M. C. Crofoot, D. Zimmerman, and S. Murray conducted fieldwork and collected samples; S. Murray and D. Zimmerman analyzed samples. L. C. Hayek and J. C. Kishbaugh analyzed the data. D. A. Tunseth, M. Mutinda, D. Zimmerman, and M. C. Crofoot wrote the manuscript; all other authors provided editorial advice.

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Authors and Affiliations

  1. Kenya Wildlife Service, Nairobi, Kenya

    Mathew Mutinda

  2. Department of Anthropology, University of California Davis, Davis, CA, 95616-8522, USA

    Margaret C. Crofoot

  3. Animal Behavior Graduate Group, University of California Davis, Davis, CA, 95616-8522, USA

    Margaret C. Crofoot

  4. Smithsonian Tropical Research Institute, Balboa, Ancon, Panama, Republic of Panama

    Margaret C. Crofoot

  5. Smithsonian Institution, National Zoological Park, Smithsonian Global Health Program, Washington, DC, 20008, USA

    Jennifer C. Kishbaugh, Dawn Zimmerman, Devin A. Tunseth & Suzan Murray

  6. Smithsonian Institution, National Museum of Natural History, Washington, DC, 20013-7012, USA

    Lee-Ann C. Hayek

Authors
  1. Mathew Mutinda
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  2. Margaret C. Crofoot
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  3. Jennifer C. Kishbaugh
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  4. Lee-Ann C. Hayek
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  5. Dawn Zimmerman
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  6. Devin A. Tunseth
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  7. Suzan Murray
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Corresponding authors

Correspondence to Margaret C. Crofoot or Jennifer C. Kishbaugh.

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Handling Editor: Joanna M. Setchell

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Mutinda, M., Crofoot, M.C., Kishbaugh, J.C. et al. Blood Biochemical Reference Intervals for Free-Ranging Olive Baboons (Papio anubis) in Kenya. Int J Primatol 40, 187–196 (2019). https://doi.org/10.1007/s10764-018-0074-2

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  • DOI: https://doi.org/10.1007/s10764-018-0074-2

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