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Inflammation

, 31:391 | Cite as

Synergistic Effect of Kalpaamruthaa on Antiarthritic and Antiinflammatory Properties—Its Mechanism of Action

  • Rajendran Mythilypriya
  • Palanivelu Shanthi
  • Panchanadam Sachdanandam
Article

Abstract

The present study was designed to evaluate the antiinflammatory properties of Kalpaamruthaa (KA) a modified indigenous Siddha formulation constituting Semecarpus anacardium nut milk extract (SA), Emblica officinalis (EO) and honey in acute and chronic antiinflammatory studies. A dose of 150 mg/kg b.wt. of SA and KA were used for the present studies. The effect of KA was compared with standard drug diclofenac sodium. It was observed that the drug KA exhibited enhanced effect on antiinflammatory and antiarthritic properties than sole SA treatment and the collective effect of KA might be due to the combined interactions of the phytochemicals such as flavonoids, tannins and other compounds such as vitamin c present in KA.

KEY WORDS

Semecarpus anacardium nut Emblica officinalis inflammation rheumatoid arthritis adjuvant induced arthritis 

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Rajendran Mythilypriya
    • 1
  • Palanivelu Shanthi
    • 2
  • Panchanadam Sachdanandam
    • 1
  1. 1.Department of Medical Biochemistry, Dr. ALM. Post Graduate Institute of Basic Medical SciencesUniversity of MadrasChennaiIndia
  2. 2.Department of Pathology, Dr. ALM. Post Graduate Institute of Basic Medical SciencesUniversity of MadrasChennaiIndia

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