Human Physiology

, Volume 31, Issue 2, pp 237–238 | Cite as

Fluctuations of the antianxiety effect of valerian and Grandaxin during daytime wakefulness in humans with different chronotypes

  • E. B. Arushanyan
  • O. A. Mastyagina
  • S. S. Mastyagin
  • A. P. Popova
Short Communications


Young people with the morning and the evening chronotypes proved to differ in the anxiety level at the beginning and the end of daytime wakefulness. The antianxiety effects of valerian and Grandaxin differed in the morning and the evening and depended on the chronotype of a subject.


Young People Human Physiology Anxiety Level Antianxiety Effect Daytime Wakefulness 


  1. 1.
    Doskin, V.A. and Lavrent’eva, N.A., Ritmy zhizni (Rhythms of Life), Moscow: Meditsina, 1991.Google Scholar
  2. 2.
    Kolkuhun, P., Working Capacity Rhythms, in Biologicheskie ritmy (Biological Rhythms), Moscow: Mir, 1984, vol. 1, p. 389.Google Scholar
  3. 3.
    Folkard, S., Circadian Rhythms and Human Memory, Chronobiologia, 1979, vol. 6, no.2, p. 88.Google Scholar
  4. 4.
    Rusak, B. and Zucker, I., Biological Rhythms and Animal Behavior, Ann. Rev. Psychol., 1975, vol. 26, p. 137.Google Scholar
  5. 5.
    Adan, A., Chronotype and Personality Factors in the Daily Consumption of Alcohol and Psychostimulants, Addiction, 1994, vol. 89, no.4, p. 455.Google Scholar
  6. 6.
    Taillard, J., Philip, P., and Bioulac, B., Morningness/Eveningness and the Need for Sleep, J. Sleep Res., 1999, vol. 8, p. 291.Google Scholar
  7. 7.
    Horne, J.A. and Ostberg, O., A Self-Assessment Questionnaire to Determine Morningness/Eveningness in Human Circadian Rhythms, Int. J. Chronobiol., 1976, vol. 4, p. 97.Google Scholar
  8. 8.
    Prakticheskaya psikhodiagnostika (Practical Psychodiagnostics), Samara: Bakhrakh, 1998.Google Scholar
  9. 9.
    Arushanyan, E.B., Anksioliticheskie sredstva (Anxiolytic Agents), Stavropol’, 2002.Google Scholar

Copyright information

© MAIK “Nauka/Interperiodica” 2005

Authors and Affiliations

  • E. B. Arushanyan
    • 1
  • O. A. Mastyagina
    • 1
  • S. S. Mastyagin
    • 1
  • A. P. Popova
    • 1
  1. 1.Medical AcademyStavropolRussia

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