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Autonomic nervous system in Takotsubo syndrome

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Abstract

Takotsubo syndrome (TTS) is an acute and usually reversible heart failure syndrome with symptoms resembling acute myocardial infarction, however, without obstruction of coronary arteries. In the majority of cases, TTS is preceded by emotional or physical stress and the disease concerns mainly postmenopausal women. Although several hypotheses have been introduced, the pathogenesis of TTS is controversial and still remains to be determined. As reported in recent studies, the role of the autonomic nervous system (ANS) seems to be pivotal in the pathogenesis of TTS. Therefore, the aim of this article is to summarize and discuss the current knowledge of the pathogenesis of TTS with a special focus on the ANS.

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  1. Department of Experimental and Clinical Physiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, 1b Banacha Street, 02-097, Warsaw, Poland

    Sonia Borodzicz, Katarzyna Czarzasta & Agnieszka Cudnoch-Jędrzejewska

  2. 1st Chair and Department of Cardiology, Medical University of Warsaw, Warsaw, Poland

    Sonia Borodzicz & Grzegorz Opolski

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  1. Sonia Borodzicz
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Borodzicz, S., Czarzasta, K., Opolski, G. et al. Autonomic nervous system in Takotsubo syndrome. Heart Fail Rev 24, 101–108 (2019). https://doi.org/10.1007/s10741-018-9729-5

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