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Flow-mediated dilation and heart failure: a review with implications to physical rehabilitation

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A Correction to this article was published on 11 November 2019

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Abstract

Endothelial dysfunction plays as an important role on mismatch responses that occur during exercise in patients with congestive heart failure (CHF). However, cardiac rehabilitation, a core component of management of CHF patients, can improve endothelial function, contributing to reduce the morbidity and mortality of these patients. The primary aims of this review were to describe the importance of flow-mediated dilatation (FMD) as a non-invasive validation tool to assess endothelial dysfunction and to highlight the relevance of scientific studies that evaluated the effects of exercise interventions on peripheral vascular endothelial function as measured by FMD in patients with CHF with both preserved and reduced ejection fraction.

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  • 11 November 2019

    The scholarship support information in Acknowledgement was missing.

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Authors and Affiliations

  1. Physiological Science Departament, Universidade Federal do Amazonas, Manaus, Brazil

    G. P. T. Areas

  2. Cardiopulmonary Physiotherapy Laboratory, Universidade Federal de Sao Carlos, Rod. Washington Luis, km 235–SP-310–CEP: 13565-905, Sao Carlos, Sao Paulo, Brazil

    G. P. T. Areas, A. Mazzuco, F. R. Caruso & A. Borghi-Silva

  3. Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil

    R. B. Jaenisch

  4. Biomedical Engineering, Politecnico di Milano, Milan, Italy

    R. Cabiddu

  5. University of Illinois at Chicago, Chicago, IL, USA

    S. A. Phillips & R. Arena

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Areas, G.P.T., Mazzuco, A., Caruso, F.R. et al. Flow-mediated dilation and heart failure: a review with implications to physical rehabilitation. Heart Fail Rev 24, 69–80 (2019). https://doi.org/10.1007/s10741-018-9719-7

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