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Glycoconjugate Journal

, Volume 32, Issue 8, pp 559–574 | Cite as

Fluorescently labelled glycans and their applications

  • Hongbin Yan
  • Ravi Shekar Yalagala
  • Fengyang Yan
Review

Abstract

This review summarises the literature on the synthesis and applications of fluorescently labelled carbohydrates. Due to the sensitivity of fluorescent detection, this approach provides a useful tool to study processes involving glycans. A few general categories of labelling are presented, in situ labelling of carbohydrates with fluorophores, fluorescently labelled glycolipids, fluorogenic glycans, pre-formed fluorescent glycans for intracellular applications, glycan-decorated fluorescent polymers, fluorescent glyconanoparticles, and other functional fluorescent glycans.

Keywords

Fluorescent labelling Glycan Carbohydrate detection Fluorogenic glycoside Fluorescent polymer Glyconanoparticle Lectin Fluorescently labelled glycolipid 

Notes

Acknowledgments

Work in Yan’s laboratory was funded by the Natural Science and Engineering Research Council of Canada. The authors wish to thank Dr. Dennis Whitefield for helpful suggestions.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Hongbin Yan
    • 1
  • Ravi Shekar Yalagala
    • 1
  • Fengyang Yan
    • 2
  1. 1.Department of ChemistryBrock UniversitySt. CatharinesCanada
  2. 2.Sussex Research Laboratories Inc.OttawaCanada

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