Glycoconjugate Journal

, Volume 32, Issue 7, pp 455–464 | Cite as

Lipo-chitooligosaccharidic nodulation factors and their perception by plant receptors



Lipo-chitooligosaccharides produced by nitrogen-fixing rhizobia are signaling molecules involved in the establishment of an important agronomical and ecological symbiosis with plants. These compounds, known as Nod factors, are biologically active on plant roots at very low concentrations indicating that they are perceived by specific receptors. This article summarizes the main strategies developed for the syntheses of bioactive Nod factors and their derivatives in order to better understand their mode of perception. Different Nod factor receptors and LCO-binding proteins identified by genetic or biochemical approaches are also presented, indicating perception mechanisms that seem to be more complicated than expected, probably involving multi-component receptor complexes.


Lipo-chitooligosaccharides Symbiosis Receptor Plant LysM 



We thank C. Gough and J. Cullimore (LIPM, Toulouse) for critical reading of the manuscript. We acknowledge funding on LCO signaling in our group by the the French National Research Agency contracts “SYMNALING” (ANR-12-BSV7-0001) and “NICE CROPS” (ANR-14-CE18-0008) and by the French Laboratory of Excellence project "TULIP" (ANR-10-LABX-41; ANR-11-IDEX-0002-02).

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.INRA, Laboratoire des Interactions Plantes-Microorganismes (LIPM), UMR441Castanet-TolosanFrance
  2. 2.CNRS, Laboratoire des Interactions Plantes-Microorganismes (LIPM), UMR2594Castanet-TolosanFrance

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