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Significant rate accelerated synthesis of glycosyl azides and glycosyl 1,2,3-triazole conjugates

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Abstract

An efficient and significantly rapid access of a series of glycosyl azides and glycosyl 1,2,3-triazole conjugates is reported using modified one-pot reaction conditions. In both cases yields were excellent and single diastereomers were obtained.

Rapid preparation of 4-substituted glycosyl 1,2,3-triazole conjugates from glycosyl bromides.

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Acknowledgments

Instrumentation facilities from SAIF, CDRI is gratefully acknowledged. R.K. thanks CSIR, New Delhi for providing a Senior Research Fellowship. This project was partly funded by Ramanna Fellowship (AKM), Department of Science and Technology (DST), New Delhi, India.

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Authors and Affiliations

  1. Molecular and Structural Biology, Central Drug Research Institute, Chattar Manzil Palace, Lucknow, 226001, UP, India

    Rishi Kumar & Prakas R. Maulik

  2. Medicinal and Process Chemistry Division, Central Drug Research Institute, Chattar Manzil Palace, Lucknow, 226001, UP, India

    Anup Kumar Misra

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  1. Rishi Kumar
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  2. Prakas R. Maulik
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  3. Anup Kumar Misra
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Correspondence to Anup Kumar Misra.

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CDRI communication no. 7340.

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Kumar, R., Maulik, P.R. & Misra, A.K. Significant rate accelerated synthesis of glycosyl azides and glycosyl 1,2,3-triazole conjugates. Glycoconj J 25, 595–602 (2008). https://doi.org/10.1007/s10719-007-9093-5

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  • DOI: https://doi.org/10.1007/s10719-007-9093-5

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