Fish Physiology and Biochemistry

, Volume 30, Issue 3–4, pp 201–211 | Cite as

Extranuclear Histones in Teleost Gills: An Evolutionary Study

  • F. M. A. H. Schuurmans Stekhoven
  • S. E. Wendelaar Bonga
  • G. Flik


Extranuclear histones and histone fragments (13–15 kDa) in gill microsomes of a phylogenetic series of teleostean fishes (tilapia, trout, carp, eel and elephant fish) were studied. Histones H2A and H2B are the first occurring of these antimicrobial agents. Halfway the evolution of teleosts (carp, trout) H3 fragments emerge, which disappear in later stages of development and are replaced by truncated H1 (tilapia). The hypothesis is forwarded that variation in composition of extranuclear histones is caused by changes in specificity of histone transporters.


Evolutionary Developments Extranuclear Histones Teleost Gills 


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Copyright information

© Springer 2005

Authors and Affiliations

  • F. M. A. H. Schuurmans Stekhoven
    • 1
  • S. E. Wendelaar Bonga
    • 1
  • G. Flik
    • 1
  1. 1.Department of Animal Physiology, Faculty of ScienceRadboud University NijmegenNijmegenThe Netherlands

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