European Journal of Epidemiology

, Volume 32, Issue 7, pp 627–629 | Cite as

The combined association of alcohol consumption with dementia risk is likely biased due to lacking account of death cases

  • Nadine Binder
  • Lisa Manderscheid
  • Martin Schumacher


Dementia Alcohol Consumption Relative Risk Estimate Death Case Moderate Alcohol Consumption 



Nadine Binder is supported by the German Research Foundation (DFG), Grant Number SCHU 756/12-2.


  1. 1.
    Xu W, Wang H, Wan Y, Tan C, Li J, Tan L, Yu JT. Alcohol consumption and dementia risk: a dose-response meta-analysis of prospective studies. Eur J Epidemiol. 2017;32(1):31–42.CrossRefPubMedGoogle Scholar
  2. 2.
    Leffondré K, Touraine C, Helmer C, Joly P. Interval-censored time-to-event and competing risk with death: is the illness-death model more accurate than the Cox model? Int J Epidemiol. 2013;42(4):1177–86.CrossRefPubMedGoogle Scholar
  3. 3.
    Lemeshow S, Letenneur L, Dartigues JF, Lafont S, Orgogozo JM, Commenges D. Illustration of analysis taking into account complex survey considerations: the association between wine consumption and dementia in the PAQUID study. Personnes Ages Quid. Am J Epidemiol. 1998;148(3):298–306.CrossRefPubMedGoogle Scholar
  4. 4.
    Orgogozo JM, Dartigues JF, Lafont S, Letenneur L, Commenges D, Salamon R, Renaud S, Breteler MB. Wine consumption and dementia in the elderly: a prospective community study in the Bordeaux area. Rev Neurol (Paris). 1997;153(3):185–92.Google Scholar
  5. 5.
    Paganini-Hill A, Kawas CH, Corrada MM. Lifestyle factors and dementia in the oldest-old: the 90+ study. Alzheimer Dis Assoc Disord. 2016;30(1):21–6.CrossRefPubMedPubMedCentralGoogle Scholar
  6. 6.
    Langballe EM, Ask H, Holmen J, Stordal E, Saltvedt I, Selbæk G, et al. Alcohol consumption and risk of dementia up to 27 years later in a large, population-based sample: the HUNT study, Norway. Eur J Epidemiol. 2015;30(9):1049–56.Google Scholar
  7. 7.
    Handing EP, Andel R, Kadlecova P, Gatz M, Pedersen NL. Midlife alcohol consumption and risk of dementia over 43 years of follow-up: a population-based study from the Swedish Twin Registry. J Gerontol Ser A Biol Sci Med Sci. 2015;70(10):1248–54.CrossRefGoogle Scholar
  8. 8.
    Zhou S, Zhou R, Zhong T, Li R, Tan J, Zhou H. Association of smoking and alcohol drinking with dementia risk among elderly men in China. Curr Alzheimer Res. 2014;11(9):899–907.PubMedPubMedCentralGoogle Scholar
  9. 9.
    Jarvenpaa T, Rinne JO, Koskenvuo M, Raiha I, Kaprio J. Binge drinking in midlife and dementia risk. Epidemiology. 2005;16(6):766–71.CrossRefPubMedGoogle Scholar
  10. 10.
    Anttila T, Helkala EL, Viitanen M, Kåreholt I, Fratiglioni L, Winblad B, et al. Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study. BMJ. 2004;329(7465):539.Google Scholar
  11. 11.
    Mukamal KJ, Kuller LH, Fitzpatrick AL, Longstreth WT Jr, Mittleman MA, Siscovick DS. Prospective study of alcohol consumption and risk of dementia in older adults. J Am Med Assoc. 2003;289(11):1405–13.CrossRefGoogle Scholar
  12. 12.
    Truelsen T, Thudium D, Gronbaek M. Amount and type of alcohol and risk of dementia: the Copenhagen City Heart Study. Neurology. 2002;59(9):1313–9.CrossRefPubMedGoogle Scholar
  13. 13.
    Ruitenberg A, van Swieten JC, Witteman JC, Mehta KM, van Duijn CM, Hofman A, et al. Alcohol consumption and risk of dementia: the Rotterdam Study. Lancet. 2002;359(9303):281–6.Google Scholar
  14. 14.
    Espeland MA, Gu L, Masaki KH, Langer RD, Coker LH, Stefanick ML, et al. Association between reported alcohol intake and cognition: results from the Women’s Health Initiative Memory Study. Am J Epidemiol. 2005;161(3):228–38.Google Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2017

Authors and Affiliations

  1. 1.Institute for Prevention and Cancer EpidemiologyFaculty of Medicine and Medical Center - University of FreiburgFreiburgGermany
  2. 2.Institute for Medical Biostatistics, Epidemiology and InformaticsUniversity Medical Center MainzMainzGermany
  3. 3.Institute for Medical Biometry and StatisticsFaculty of Medicine and Medical Center - University of FreiburgFreiburgGermany

Personalised recommendations