European Journal of Epidemiology

, Volume 32, Issue 2, pp 145–158 | Cite as

The LIFE Child study: a population-based perinatal and pediatric cohort in Germany

  • Tanja Poulain
  • Ronny Baber
  • Mandy Vogel
  • Diana Pietzner
  • Toralf Kirsten
  • Anne Jurkutat
  • Andreas Hiemisch
  • Anja Hilbert
  • Jürgen Kratzsch
  • Joachim Thiery
  • Michael Fuchs
  • Christian Hirsch
  • Franziska G. Rauscher
  • Markus Loeffler
  • Antje Körner
  • Matthias Nüchter
  • Wieland Kiess
  • the LIFE Child study team


The LIFE Child study is a large population-based longitudinal childhood cohort study conducted in the city of Leipzig, Germany. As a part of LIFE, a research project conducted at the Leipzig Research Center for Civilization Diseases, it aims to monitor healthy child development from birth to adulthood and to understand the development of lifestyle diseases such as obesity. The study consists of three interrelated cohorts; the birth cohort, the health cohort, and the obesity cohort. Depending on age and cohort, the comprehensive study program comprises different medical, psychological, and sociodemographic assessments as well as the collection of biological samples. Optimal data acquisition, process management, and data analysis are guaranteed by a professional team of physicians, certified study assistants, quality managers, scientists and statisticians. Due to the high popularity of the study, more than 3000 children have already participated until the end of 2015, and two-thirds of them participate continuously. The large quantity of acquired data allows LIFE Child to gain profound knowledge on the development of children growing up in the twenty-first century. This article reports the number of available and analyzable data and demonstrates the high relevance and potential of the study.


Longitudinal study Cohort study Children Obesity Pregnancy Epidemiology 



This publication is supported by LIFE – Leipzig Research Center for Civilization Diseases, University of Leipzig. LIFE is funded by means of the European Union, by means of the European Social Fund (ESF), by the European Regional Development Fund (ERDF), and by means of the Free State of Saxony within the framework of the excellence initiative. The Integrated Research and Treatment Center Adiposity Diseases is funded by the German Federal Ministry of Education and Research (Grant 01EO1501).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants are in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent is obtained from all individual participants included in the study.

Supplementary material

10654_2016_216_MOESM1_ESM.pdf (161 kb)
Supplementary material 1 (PDF 161 kb)


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Copyright information

© Springer Science+Business Media Dordrecht 2017

Authors and Affiliations

  • Tanja Poulain
    • 1
  • Ronny Baber
    • 1
    • 2
  • Mandy Vogel
    • 1
  • Diana Pietzner
    • 1
  • Toralf Kirsten
    • 1
  • Anne Jurkutat
    • 1
  • Andreas Hiemisch
    • 1
    • 3
  • Anja Hilbert
    • 4
    • 5
  • Jürgen Kratzsch
    • 2
  • Joachim Thiery
    • 2
  • Michael Fuchs
    • 6
  • Christian Hirsch
    • 7
  • Franziska G. Rauscher
    • 8
  • Markus Loeffler
    • 1
    • 9
  • Antje Körner
    • 1
    • 3
    • 4
  • Matthias Nüchter
    • 1
  • Wieland Kiess
    • 1
    • 3
    • 4
  • the LIFE Child study team
  1. 1.LIFE Leipzig Research Center for Civilization DiseasesUniversity of LeipzigLeipzigGermany
  2. 2.Institute of Laboratory Medicine, Clinical Chemistry, and Molecular Diagnostics (ILM)University of LeipzigLeipzigGermany
  3. 3.Department of Women and Child Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL)University of LeipzigLeipzigGermany
  4. 4.Integrated Research and Treatment Center Adiposity DiseasesUniversity of LeipzigLeipzigGermany
  5. 5.Department of Medical Psychology and Medical SociologyUniversity of LeipzigLeipzigGermany
  6. 6.Section of Phoniatrics and Audiology, Department of OtorhinolaryngologyUniversity of LeipzigLeipzigGermany
  7. 7.Department of Pediatric and Preventive DentistryUniversity of LeipzigLeipzigGermany
  8. 8.Department of OphthalmologyUniversity of LeipzigLeipzigGermany
  9. 9.Institute for Medical Informatics, Statistics, and EpidemiologyUniversity of LeipzigLeipzigGermany

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