Incidence and prediction of falls in Parkinson’s disease: a prospective cohort study
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Falls represent continuing, disabling and costly problem in Parkinson’s disease (PD) . In a long-term prospective study of PD patients, after 20 years of follow-up, at least one fall occurred in 81 % of participants of whom 23 % sustained a fracture . Fall-related burden in PD has substantial impact on activity limitations, participation restrictions, social isolation or premature mortality .
Various studies have indicated that age, longer disease duration, advanced stages of the disease, poor balance, freezing of gait, lower extremity weakness, fear of falling and depression, were independently associated with falling in PD . However, precise quantification of risk for falling in PD is still missing. Previous studies dealing with the risk factors for falls in PD expressed incidence by means of incidence proportions . At the same time, the concept of person-time at risk of falling, that includes individual contribution of observed time during which falls occurred, has...
KeywordsHamilton Depression Rate Scale Incidence Density Hamilton Anxiety Rate Scale Levodopa Dose Equivalency Incidence Proportion
This investigation was supported by the Ministry of Education and Science of the Republic of Serbia (Grants No 175087 and 175090).
- 4.Gazibara T, Pekmezovic T, Kisic Tepavcevic D, Tomic A, Stankovic I, Kostic VS et al. Fall frequency and risk factors in patients with Parkinson’s disease in Belgrade, Serbia: a cross-sectional study. Geriatr Gerontol Int. 2014. doi: 10.1111/ggi.12300.
- 7.Gazibara T, Stankovic I, Tomic A, Svetel M, Tepavcevic DK, Kostic VS et al. Validation and cross-cultural adaptation of the Self-Assessment Disability Scale in patients with Parkinson’s disease in Serbia. J Neurol. 260(8):1970-7.Google Scholar
- 9.Allen NE, Schwarzel AK, Canning CG. Recurrent falls in Parkinson’s disease: a systematic review. Park Dis. 2013;2013:906274.Google Scholar