European Journal of Epidemiology

, Volume 29, Issue 1, pp 73–76 | Cite as

Chemical accident at Hoechst AG Frankfurt/Main, Germany, 1993: a 15 year follow-up analysis of mortality

  • Veronika Weyer
  • Maria Blettner
  • Constanze Cholmakow-Bodechtel
  • Ursel Heudorf
Letter to the Editor

On 22nd February 1993 a major chemical accident occurred at the chemical plant of the Hoechst AG Frankfurt (Main), Germany (FFM). Approximately twelve tons of a complex chemical mixture [27 different substances, many of them nitroarenes; main substance o-nitroanisole (ONA)] were released into the air via a safety-valve. A part of the substance came down as “yellow rain” and lead to severe contamination in an area of allotment-gardens (up to 2,000 mg ONA/m2) and in a nearby housing area in the district Schwanheim near FFM. Soil samples were taken in several parts of the area. Cleaning and redevelopment measures started promptly after the accident. One month later no more contamination was detected in the district of Schwanheim. Further details of the pollution see [1].

Short-term health effects of the accident had been documented in 83 adults and 15 children and were reported [2]. Neurotoxic, cardiotoxic, and hematotoxic effects of nitroarenes were not observed [3].

Some of the...


Cancer Mortality Standardize Mortality Ratio Specific Cancer Site Reference Zone Chemical Accident 
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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Veronika Weyer
    • 1
  • Maria Blettner
    • 1
  • Constanze Cholmakow-Bodechtel
    • 2
  • Ursel Heudorf
    • 3
  1. 1.Institute of Medical Biostatistics, Epidemiology and InformaticsUniversity Medical Center MainzMainzGermany
  2. 2.Kantar Health GmbHMunichGermany
  3. 3.Public Health Department of the City of Frankfurt/MainFrankfurtGermany

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