Chemical accident at Hoechst AG Frankfurt/Main, Germany, 1993: a 15 year follow-up analysis of mortality
- 190 Downloads
On 22nd February 1993 a major chemical accident occurred at the chemical plant of the Hoechst AG Frankfurt (Main), Germany (FFM). Approximately twelve tons of a complex chemical mixture [27 different substances, many of them nitroarenes; main substance o-nitroanisole (ONA)] were released into the air via a safety-valve. A part of the substance came down as “yellow rain” and lead to severe contamination in an area of allotment-gardens (up to 2,000 mg ONA/m2) and in a nearby housing area in the district Schwanheim near FFM. Soil samples were taken in several parts of the area. Cleaning and redevelopment measures started promptly after the accident. One month later no more contamination was detected in the district of Schwanheim. Further details of the pollution see .
Short-term health effects of the accident had been documented in 83 adults and 15 children and were reported . Neurotoxic, cardiotoxic, and hematotoxic effects of nitroarenes were not observed .
Some of the...
KeywordsCancer Mortality Standardize Mortality Ratio Specific Cancer Site Reference Zone Chemical Accident
- 2.Hahn A, Michalak M, Noack K, Wolski M, Heinemeyer G, Heudorf U, Peters M: Nitroanisol accident at Hoechst AG, Frankfurt/Main, Germany February 1993. Assessment of Health Problems with Information of Posonings by the Chemicals Act. Abstract-Band des Scientific Meeting Krakau: European Associations of Poison-Centers and Clinical Toxicologists, Krakau. 1996.Google Scholar
- 3.Schuckmann F, Mayer D. Chemical accident in Hoechst AG—plant Griesheim. Aspects on toxicology, occupational and environmental medicine. Der Störfall im Hoechst-Werk Griesheim. Hessisches Ärzteblatt. 1993;54:87–8.Google Scholar
- 5.Neumann P. Chemical accident at Hoechst AG, February 22nd, 1993. Health assessment studies. Expert opinion, July 22nd 1996. Published in: Public health department of the city of Frankfurt/M: Chemical accident at Hoechst AG Frankfurt/Main February 22nd 1993. 1996. Exposure registry of the Bremen Institute for Prevention Research and Social medicine (BIPS): History and current data Frankfurt 2001.Google Scholar
- 6.Breslow NE, Day NE. Statistical methods in cancer research. Volume II—the design and analysis of cohort studies. IARC Sci Publ. 1987;82:1–406.Google Scholar
- 7.IARC. 2-Nitroanisole. In Printing Processes and Printing inks, Carbon black and Some Nitro Compounds. 1996.Google Scholar