European Journal of Epidemiology

, Volume 21, Issue 1, pp 77–81 | Cite as

Seroprevalence of Anti-Yersinia Antibodies in Healthy Austrians

  • H. Tomaso
  • G. Mooseder
  • S. Al Dahouk
  • C. Bartling
  • H. C. Scholz
  • R. Strauss
  • T. M. Treu
  • H. Neubauer
Infectious Diseases


Yersiniosis is caused by Y. enterocolitica and Y. pseudotuberculosis mostly presenting as intestinal infection. The infection is usually acquired from contaminated food. The aim of this study was to determine the seroprevalence of anti-Yersinia antibodies in Austrians. Sera of 750 healthy Austrians from all nine states were tested for anti-Yersinia IgG antibodies using the recomBlot Yersinia Westernblot® kit. Overall seroprevalence was 29.7%. Seroprevalence increased significantly with age from 24.7% in the group of the 19 to 24 year olds to 38.5% in the group of persons older than 44 years. The seroprevalence of anti-Yersinia antibodies varied within the states between 18% and 43.5%. The high seroprevalence of anti-Yersinia antibodies in contrast to only approximately 100 reported yersiniosis cases per year points to the fact that the majority of infections is either subclinical or mild.


seroprevalence Yersinia westernblot Austria 


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  1. 1.
    Aleksic, S, Bockemühl, J. 1990Mikrobiologie und Epidemiologie der YersiniosenImmun Infekt18178185PubMedGoogle Scholar
  2. 2.
    Aleksic, S, Bockemühl, J, Wuthe, HH. 1995Epidemiology of Y. pseudotuberculosis in Germany, 1983–1993Contrib Microbiol Immunol135558PubMedGoogle Scholar
  3. 3.
    Hoogkamp-Korstanje, JAA, Koning, J. 1990Enteropathogene Yersinien: Pathogenitätsfaktoren und neue diagnostische MethodenInfekt Immun18186191Google Scholar
  4. 4.
    Prentice, M, Cope, D, Swann, RA. 1991The epidemiology of Yersinia enterocolitica infection in the British Islands 1983–1988Contr Microbiol Immunol121725Google Scholar
  5. 5.
    Tauxe, RV, Vandepitte, J, Wauters, G, Martin, SM, Gossens, V, Mol, P, Noyen, R, Thiers, G. 1987Yersinia enterocolitica infections and pork: the missing linkLancet111291132PubMedGoogle Scholar
  6. 6.
    Gourdon, F, Beytout, J, Reynaud, A, Romaszko, J-P, Perre, D, Theodore, P, Soubelet, H, Sirot, J. 1999Human and animal epidemic of Yersinia enterocolitica O:9, 1989–1997, Auvergne, FranceEmerg Infect Dis5719721PubMedGoogle Scholar
  7. 7.
    Kapperud, G, Ostroff, SM, Nesbakken, T, Hutwanger, LC, Bean, NH, Lassen, J, Tauxe, RV. 1995Risk factors for sporadic Yersinia enterocolitica infections in Norway: A case control studyContr Microbiol Immunol132528Google Scholar
  8. 8.
    Heesemann, J. 1990Enteropathogene Yersinien: Pathogenitätsfaktoren und neue diagnostische MethodenInfekt Immun18186191Google Scholar
  9. 9.
    Cornelis, GR, Boland, A, Boyd, AP, Geuijen, C, Iriarte, M, Neyt, C, Sory, M-P, Stainier, I. 1998The virulence plasmid of Yersinia, an anti host genomeMicrobiol Mol Biol Rev6213151352PubMedGoogle Scholar
  10. 10.
    Rosqvist, R, Magnusson, K-E, Wolf-Watz, H. 1994Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cellsEMBO J13964972PubMedGoogle Scholar
  11. 11.
    Andersson, K, Carballeira, N, Magnusson, K-E, Persson, C, Stendahl, O, Wolf-Watz, H, Fällmann, M. 1996YopH of Yersinia pseudotuberculosis interrupts early phosphotyrosine signalling assosiated with phagocytosisMol Microbiol2010571069PubMedGoogle Scholar
  12. 12.
    Mäki-Ikola, O, Heesemann, J, Toivanen, I, Granfors, K. 1997High frequency of Yersinia antibodies in healthy populations in Finland and GermanyRheumatol Int16227229CrossRefPubMedGoogle Scholar
  13. 13.
    Neubauer, H, Sprague, LD, Scholz, H, Hensel, A. 2001Yersinia enterolitica infections: 2. Impact on human healthBerl Munch Tierarztl Wochenschr1148187PubMedGoogle Scholar
  14. 14.
    Aleksic, S, Bockemuhl, J, Wuthe, HH, Aleksic, V. 1988Occurrence and clinical importance of the pathogenic serogroup O: 5, 27 of Yersinia enterocolitica in the Federal Republic of Germany and methods for its serological and bacteriological identificationZentralbl Bakteriol Mikrobiol Hyg [A]269197204Google Scholar
  15. 15.
    Fredriksson-Ahomaa, M, Bucher, M, Hank, C, Stolle, A, Korkeala, H. 2001High prevalence of Yersinia enterocolitica 4:O3 on pig offal in southern Germany: a slaughtering technique problemSyst Appl Microbiol24457463PubMedGoogle Scholar
  16. 16.
    Gurtler, M, Alter, T, Kasimir, S, Linnebur, M, Fehlhaber, K. 2005Prevalence of Yersinia enterocolitica in fattening pigsJ Food Prot68850854PubMedGoogle Scholar
  17. 17.
    Verhaegen, J, Charlier, J, Lemmens, P, Delmee, M, Noyen, R, Verbist, L, Wauters, G. 1998Surveillance of human Yersinia enterocolitica infections in Belgium: 1967–1996Clin Infect Dis275964PubMedGoogle Scholar
  18. 18.
    Hensel, A, Nikolaou, K, Bartling, C, Petry, T, Arnold, T, Rosler, U, Czerny, CP, Truyen, U, Neubauer, H. 2004The prevalence of anti-Yersinia outer protein antibodies in Bavarian slaughter pigsBerl Munch Tierarztl Wochenschr.1173038PubMedGoogle Scholar
  19. 19.
    Nikolaou, K, Hensel, A, Bartling, C, Tomaso, H, Arnold, T, Rosler, U, Ganter, M, Petry, T, Neubauer, H. 2005Prevalence of anti-Yersinia outer protein antibodies in goats in lower saxonyJ Vet Med B Infect Dis Vet Public Health521724PubMedGoogle Scholar
  20. 20.
    Bartling, C, Truyen, U, Isa, G, Neubauer, H. 2004The prevalence of Yersinia-specific antibodies in cattle in BavariaBerl Munch Tierarztl Wochenschr117499507PubMedGoogle Scholar
  21. 21.
    Hawari, AD, Amtsberg, G, Kirpal, G. 1981Cultural and serological studies of the occurrence of Yersinia enterocolitica infections in swine and cattleBerl Munch Tierarztl Wochenschr94404409PubMedGoogle Scholar
  22. 22.
    Pannwitz, S, Roost, H. 2001Gehäuftes Auftreten blutserologischer Brucellose-Reaktionen in einem Mastschweinebestand mit Yersinia enterocolitica- Nachweis –FallberichtTierärztl Umschau56306314Google Scholar
  23. 23.
    Thibodeau, U, Frost, EH, Quessy, S. 2001Development of an ELISA procedure to detect swine carriers of pathogenic Yersinia enterocoliticaVet Microbiol82249259CrossRefPubMedGoogle Scholar
  24. 24.
    Heesemann, J, Eggers, C, Schröder, J. 1987Serological diagnosis of yersiniosis by immunoblot technique using virulence-associated antigen of enteropathogenic YersiniaeContr Microbiol Immunol9285289Google Scholar
  25. 25.
    Heesemann, J, Gross, U, Schmidt, N, Laufs, R. 1986Immunochemical analysis of plasmid-encoded proteins released by enteropathogenic Yersinia sp. grown in calcium- deficient mediaInfect Immun54561567PubMedGoogle Scholar
  26. 26.
    Robins-Browne, RM, Bordun, AM, Slee, KJ. 1993Serological response of sheep to plasmid-encoded proteins of Yersinia species following natural infection with Y. enterocolitica and Y. pseudotuberculosisJ Med Microbiol39268272PubMedGoogle Scholar
  27. 27.
    Weynants, V, Tibor, A, Denoel, PA, Saegerman, C, Godfroid, J, Thiange, P, Letesson, JJ. 1996Infection of cattle with Yersinia enterocolitica O:9 a cause of the false positive serological reactions in bovine brucellosis diagnostic testsVet Microbiol48101112PubMedGoogle Scholar
  28. 28.
    Granfors, K, Lahesmaa-Rantala, R, Stahlberg, TH, Toivanen, A. 1989Comparison of bacteria with and without plasmid-encoded proteins as antigens for measurement of immunoglobulin M, G, and A antibodies to Yersinia enterocolitica by enzyme-linked immunosorbent assayJ Clin Microbiol27583585PubMedGoogle Scholar
  29. 29.
    Tsai, S-J, Chen, LH. 1991Occurrence of Yersinia enterocolitica in pork products from Northern TaiwanContr. Microbiol Immunol125662Google Scholar
  30. 30.
    Fukushima, H, Hoshina, K, Itogawa, H, Gomyoda, M. 1997Introduction into Japan of pathogenic Yersinia through imported pork, beef and fowlInt J Food Microbiol35205121CrossRefPubMedGoogle Scholar
  31. 31.
    Niskanen, T, Fredriksson-Ahomaa, M, Korkeala, H. 2003Occurrence of Yersinia pseudotuberculosis in iceberg lettuce and environmentAdv Exp Med Biol.529383385PubMedGoogle Scholar

Copyright information

© Springer 2006

Authors and Affiliations

  • H. Tomaso
    • 1
  • G. Mooseder
    • 2
  • S. Al Dahouk
    • 1
  • C. Bartling
    • 3
  • H. C. Scholz
    • 1
  • R. Strauss
    • 4
  • T. M. Treu
    • 5
  • H. Neubauer
    • 1
  1. 1.Bundeswehr Institute of MicrobiologyMunichGermany
  2. 2.Military Hospital ViennaViennaAustria
  3. 3.Laboratory Dr. QuadeCologneGermany
  4. 4.Federal Ministry of Health and WomenViennaAustria
  5. 5.Military Medical Training SchoolViennaAustria

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