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Severe respiratory symptoms to oxaliplatin infusion: a case report of delayed hypersensitivity reaction

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An Erratum to this article was published on 25 February 2010

Summary

A 46-year-old man with adenocarcinoma of the sigmoid colon developed a hypersensitivity reaction after the sixth cycle of combination chemotherapy with oxaliplatin infusion. Hypersensitivity to oxaliplatin occurring, after several courses of therapy, in about 10–15% of patients, especially during or immediately after the oxaliplatin infusion. In this case report we present a delayed hypersensitivity reaction, consisting in dysesthesia and laryngeal spasm developed 10 h after the sixth administration of oxaliplatin.

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Authors and Affiliations

  1. Department of Experimental Medicine, Section of Pharmacology “L. Donatelli”, Second University of Naples, Via Costantinopoli 16, 80138, Naples, Italy

    Simona Potenza, Amelia Filippelli, Francesco Rossi & Annalisa Capuano

  2. National Cancer Institute of Naples, Colorectal Department, ‘G. Pascale’ Foundation, Via M. Semmola, 80131, Naples, Italy

    Guglielmo Nasti & Ottaiano Alessandro

Authors
  1. Simona Potenza
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  2. Guglielmo Nasti
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  3. Ottaiano Alessandro
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  4. Amelia Filippelli
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  5. Francesco Rossi
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  6. Annalisa Capuano
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Corresponding author

Correspondence to Simona Potenza.

Additional information

An erratum to this article can be found at http://dx.doi.org/10.1007/s10637-010-9404-8

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Potenza, S., Nasti, G., Alessandro, O. et al. Severe respiratory symptoms to oxaliplatin infusion: a case report of delayed hypersensitivity reaction. Invest New Drugs 28, 185–186 (2010). https://doi.org/10.1007/s10637-009-9250-8

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  • DOI: https://doi.org/10.1007/s10637-009-9250-8

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