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Documenta Ophthalmologica

, Volume 111, Issue 1, pp 1–6 | Cite as

LED-generated Multifocal ERG On- and Off-responses in Complete Congenital Stationary Night Blindness – A Case Report

  • Dorothee Leifert
  • Margarita G. Todorova
  • Chrisitan Prünte
  • Anja M. Palmowski-Wolfe
Article

Abstract

We report on the application of a light emitting diode (LED) screen to elicit multifocal ERG on- and off-responses in a patient presenting with the complete type of congenital stationary night blindness (cCSNB): A 63-years old woman was diagnosed with cCSNB by means of standard ERG procedures and dark adaptometry. To confirm this diagnosis and to investigate topographical differences of on- and off-responses a multifocal approach employing long-duration stimuli was added. Results of mfERG-testing were averaged in three groups (a central area of 7.5°, a ring area of 7.5–21.9° and a peripheral ring of 21.9–31.1°). When compared to normal controls (n = 4) on-responses (P1-amplitudes) were severely reduced symmetrically at all eccentricities, while off-responses showed no reduction resulting in an increased off/on-ratio. Furthermore on-latencies of P1 were delayed symmetrically at all eccentricities, whereas off-latencies were normal. To our knowledge this is the first report of multifocal on- and off-responses in a CSNB-patient. Stimulus-generation with a LED-screen provides the advantage of a stable luminance during the long-duration on-phase.

Keywords

LED multifocal ERG night blindness on- and off-response 

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Copyright information

© Springer 2006

Authors and Affiliations

  • Dorothee Leifert
    • 1
  • Margarita G. Todorova
    • 1
  • Chrisitan Prünte
    • 1
  • Anja M. Palmowski-Wolfe
    • 1
  1. 1.Department of OphthamlologyUniversity Hospital BaselBaselSwitzerland

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