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Impact on Health-Related Quality of Life in Adults with Eosinophilic Gastritis and Gastroenteritis: A Qualitative Assessment

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Abstract

Background

Eosinophilic gastritis (EG) and eosinophilic gastroenteritis (EGE) are chronic immune-mediated conditions of the digestive tract, which affect the stomach only, or the stomach and small intestines, respectively. Though these disorders are uncommon, they are being increasingly recognized and diagnosed. While health-related quality of life (HRQOL) has been evaluated in other eosinophilic gastrointestinal diseases, this study is the first to describe HRQOL impacts unique to EG/EGE.

Aims

This study aims to qualitatively describe experiences of adults diagnosed with EG and EGE. We aim to identify impacts on HRQOL in this population in order to inform clinical care and assessment.

Methods

Seven patients diagnosed with EG or EGE participated in semi-structured interviews assessing common domains of HRQOL.

Results

Four distinct themes emerged from qualitative analyses, which represent impacts to HRQOL: the psychological impact of the diagnosis, impact on social relationships, financial impact, and impact on the body. These generally improved over time and with effective treatment.

Conclusions

This study demonstrated that patients with EG/EGE experience impacts to HRQOL, some of which differ from HRQOL of other eosinophilic gastrointestinal diseases. These results support the development of a disease-specific measure, or adaptation of an existing measure, to assess HRQOL in EG/EGE.

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Funding

Ms. Craven and Ms. Guadagnoli are supported by the T32DK101363 Training Grant in GI Physiology and Psychology.

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Authors and Affiliations

  1. Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, 676 N. Saint Clair St. #1400, Chicago, IL, 60611, USA

    Alyse Bedell, Tiffany Taft, Meredith R. Craven, Livia Guadagnoli, Ikuo Hirano & Nirmala Gonsalves

Authors
  1. Alyse Bedell
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  2. Tiffany Taft
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  3. Meredith R. Craven
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  4. Livia Guadagnoli
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  5. Ikuo Hirano
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  6. Nirmala Gonsalves
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Correspondence to Alyse Bedell.

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The authors have nothing to disclose and no competing interests.

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Bedell, A., Taft, T., Craven, M.R. et al. Impact on Health-Related Quality of Life in Adults with Eosinophilic Gastritis and Gastroenteritis: A Qualitative Assessment. Dig Dis Sci 63, 1148–1157 (2018). https://doi.org/10.1007/s10620-018-4978-7

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  • DOI: https://doi.org/10.1007/s10620-018-4978-7

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