Digestive Diseases and Sciences

, Volume 59, Issue 10, pp 2503–2507 | Cite as

A Rapid and Accurate Method to Detect Active Small Bowel Gastrointestinal Bleeding on Video Capsule Endoscopy

  • Adam C. Stein
  • Anoop Appannagari
  • Ibrahim Habib
  • Carol E. Semrad
  • David T. Rubin
Original Article



Video capsule endoscopy (VCE) is indicated to evaluate for suspected small bowel bleeding, but “standard view” (SV) evaluation is time-consuming. Rapid Reader 6.0 software (Given Imaging, Duluth GA) contains two computer algorithmic systems: (1) “Quickview” (QV) which automatically skips similar images and (2) a pixel analysis program that identifies suspected blood (SBI). Combining the two modalities (QV + SBI) may provide a faster modality to assess for active small bowel bleeding.


This study was designed to assess the accuracy of QV + SBI for small bowel bleeding compared to SV findings.


This is a retrospective, case–control study at a single tertiary care referral hospital including all patients with VCE performed for suspected small bowel bleeding from 4/2007 to 3/2011. All studies were previously read using SV by one of two experienced faculty (CS, DR). The primary outcome was diagnostic accuracy of QV + SBI in assessing for active small bowel bleeding compared to SV.


A total of 116 VCE were included, 28 with active small bowel bleeding identified by original SV. Using QV + SBI, all 28 VCEs with active small bowel bleeding were identified. The sensitivity of QV + SBI to detect active bleeding was 100 %, while the specificity was 93–94 %. The mean time to identify landmarks and read the entire study was 3 min 20 s.


The QV + SBI reading format of VCE is an efficient, highly sensitive modality to assess for potential small bowel bleeding.


Video capsule endoscopy Small bowel bleeding Quickview Suspected blood indicator Given 


Conflict of interest

Carol E. Semrad—has received consulting fees from Given Imaging. David T. Rubin—has received consulting fees from Given Imaging. For the remaining authors none were declared.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Adam C. Stein
    • 1
  • Anoop Appannagari
    • 2
  • Ibrahim Habib
    • 3
  • Carol E. Semrad
    • 1
  • David T. Rubin
    • 1
  1. 1.Section of Gastroenterology, Hepatology, and Nutrition, Department of MedicineUniversity of Chicago MedicineChicagoUSA
  2. 2.Division of Gastroenterology, Department of MedicineLoyola UniversityMaywoodUSA
  3. 3.Department of MedicineAdvocate Lutheran General HospitalPark RidgeUSA

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