Multiple Hepatic Adenomas in a Child with Microvillus Inclusion Disease
Stanford Multidisciplinary Seminars
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Case Presentation and Evolution
The patient, who was born full term to non-consanguineous parents following a pregnancy complicated only by polyhydramnios, was admitted with severe dehydration, weight loss and diarrhea on the sixth day of life. His electrolytes were significant for sodium 149 mmol/L, potassium 5 mmol/L, chloride 130 mmol/L, and bicarbonate 4.5 mmol/L. For the next 2 months, he suffered recurrent episodes of sepsis and suspected necrotizing enterocolitis. His stool output was secretory and large volume, ranging from 100 to 200 ml/kg/day, and did not change with cessation of enteral feeds. Workup included stool cultures and serum titers negative for enteric bacteria, viral and parasitic infections, normal inflammatory markers, normal immunoglobulins and complement, normal gastrin and urine catecholamines. An endoscopic biopsy at 3 months of life showed total atrophy of the intestinal villi. Periodic acid-Schiff staining revealed targetoid structures in the cytoplasm of...
KeywordsAdenoma Total Parenteral Nutrition Glycogen Storage Disease Galactosemia Hepatocellular Adenoma
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Conflict of interest
- 15.Raman SP, Hruban RH, Fishman EK. Hepatic adenomatosis: spectrum of imaging findings. Abdominal Imaging [Internet]. 2012 May 20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22610057. Cited 21 June 2012.
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