Histologically Confirmed IgG4-Related Small Intestinal Lesions Diagnosed via Double Balloon Enteroscopy
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Immunoglobulin G4 (IgG4)-related disease is a systemic disease characterized by chronic inflammation with abundant IgG4-positive cells and elevated serum IgG4. Previous reports describe infiltration of IgG4-positive cells in multiple organs . In the gastrointestinal (GI) tract, previous reports indicate that inflammation was observed in the esophagus, stomach, and colon [1, 2, 3, 4, 5, 6]. However, there have been few reports regarding small intestinal lesions. We report a case of IgG4-related disease with small and large intestinal lesions.
KeywordsIgG4-related disorder Small intestinal lesion Balloon assist enteroscopy Immunohistochemistry
The authors would like to express thanks to Dr Joseph Onyiah for giving us fruitful comments and editing the English language.
Conflict of interest