Prevalence of Colon Polyps Detected by Colonoscopy Screening of Asymptomatic Hispanic Patients
- 219 Downloads
Compared with whites, Hispanics have lower incidence of and mortality from colorectal cancer. The purpose of this study was to determine whether asymptomatic Hispanics undergoing colonoscopy screening also have lower age-adjusted incidence of polyps ≥10 mm. Such data could be used to formulate future screening guidelines.
The objectives of this study were to measure and analyze the prevalence and location of polyps sized ≥10 mm in asymptomatic white and Hispanic patients who received colonoscopy screening.
Colonoscopy data were prospectively collected from the Clinical Outcomes Research Initiative database, which includes data from a consortium of 66 adult gastrointestinal practice sites in the United States. Asymptomatic white (n = 146,798) and Hispanic (n = 7,654) patients who received colonoscopy screening from 2004 to 2007 were identified. The prevalence of any polyps ≥10 mm and of proximal polyps ≥10 mm was adjusted for age, sex, practice site type, and family history of colorectal cancer in a multivariate analysis.
There was no significant difference between prevalence of polyps ≥10 mm in Hispanic and white patients (5.8% vs. 6.2%; P = 0.11; adjusted OR 0.94; 95% CI 0.85–1.03). There was also no significant difference between prevalence of proximal polyps ≥10 mm in Hispanics and whites (adjusted OR 1.05; 95% CI 0.87–1.27).
Despite lower incidence of colorectal cancer, the risk of polyps ≥10 mm for Hispanic patients undergoing colonoscopy screening is similar to that for whites. These data emphasize the importance of encouraging timely colorectal cancer screening in Hispanics. Our findings support the application of similar recommendations for colorectal cancer screening of Hispanics and whites.
KeywordsHispanic Colorectal cancer Colon polyps Colonoscopy Screening
This project was supported with funding from NIDDK UO1 DK57132. In addition, the practice network (Clinical Outcomes Research Initiative; CORI) has received support from the following entities to support the infrastructure of the practice-based network: AstraZeneca, Bard International, Pentax USA, ProVation, Endosoft, GIVEN Imaging, and Ethicon. The commercial entities had no involvement in this research. Dr Lieberman is the executive director of the CORI, a non-profit organization that receives funding from federal and industry sources. The CORI database was used in this study. This relationship was reviewed and managed by the OHSU and VA Conflict of Interest in Research Committees.
- 1.American Cancer Society. Colorectal Cancer Facts & Figures 2011–2013. Atlanta: American Cancer Society; 2011.Google Scholar
- 4.American Cancer Society. Cancer Facts and Figures for Hispanics/Latinos 2009–2011. Atlanta: American Cancer Society; 2009.Google Scholar
- 7.Levin B, Lieberman DA, McFarland B, et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. Gastroenterology. 2008;134:1570–1595.PubMedCrossRefGoogle Scholar
- 18.Horner MJ, Ries LAG, Krapcho M, et al., eds. SEER Cancer Statistics Review, 1975–2006. Bethesda, MD: National Cancer Institute; 2009.Google Scholar
- 20.Centers for Disease Control, Prevention (CDC). Vital signs: colorectal cancer screening among adults aged 50–75 years—United States, 2008. MMWR Morb Mortal Wkly Rep. 2010;59:808–812.Google Scholar
- 22.Klabunde CN, Cronin KA, Breen N, Waldron WR, Ambs AH, Nadel MR. Trends in colorectal cancer test use among vulnerable populations in the United States. Cancer Epidemiol Biomarkers Prev. 2011;20:1611–1621.Google Scholar
- 26.Soto-Salgado M, Suarez E, Calo W, Cruz-Correa M, Figueroa-Valles NR, Ortiz AP. Incidence and mortality rates for colorectal cancer in Puerto Rico and among Hispanics, non-Hispanic whites, and non-Hispanic blacks in the United States, 1998–2002. Cancer. 2009;115:3016–3023.PubMedCrossRefGoogle Scholar