A Rare Presentation of an Uncommon Malignancy: Thromboembolism in a Patient with a Gastrointestinal Stromal Tumor
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Gastrointestinal stromal tumors (GISTs) are uncommon, with an annual incidence of 10–20 per 106 persons . GISTs usually arise from mutations in the c-KIT receptor . Approximately 50–60% occur in the stomach and often present as an abdominal mass, pain, or gastrointestinal (GI) bleeding . We describe a patient who presented with deep vein thrombosis (DVT) and pulmonary embolism (PE) and was found to have a GIST.
A 48-year-old man presented to the emergency department with left leg pain and dyspnea on exertion that began 1 week earlier. He denied weight loss, abdominal pain, fever, or chills but reported occasional dark bowel movements. He had no history of blood clots, recent travel, or prolonged immobility.
KeywordsGIST Gastrointestinal stromal tumor Thromboembolism Deep vein thrombosis Pulmonary embolism Malignancy
Conflict of interest
There are no financial arrangements or conflicts of interest to be declared.