Celiac Disease Is Associated with Neurological Syndromes
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We read with interest the manuscript by Weinstock et al.  in which they evaluated the relationship between celiac disease and restless legs syndrome (RLS). The authors reported the incidence of RLS among 85 patients with celiac disease as 35%, with prevalence of 25%, compared with 10% of spouses (P < 0.02), and in 79% of patients with RLS and celiac disease, neuromuscular symptoms began during or after onset of gastrointestinal symptoms. They also reported that iron deficiency was present in 40% of celiac patients with active RLS compared with 6% of patients without RLS (P < 0.001) and that after 6 months of a gluten-free diet, RLS symptoms improved in 50% of 28 patients. They concluded that screening for celiac disease in patients with RLS is important, because celiac disease is commonly an overlooked silent disease and may be a correctable factor for some patients with idiopathic RLS.
We would like to report two cases of silent celiac disease, with complaints of non-specific...
KeywordsCreatine Kinase Celiac Disease Myopathy Iron Deficiency Anemia Neurological Finding