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Digestive Diseases and Sciences

, Volume 54, Issue 4, pp 816–818 | Cite as

Aperitif Effects on Gastric Emptying: A Crossover Study Using Continuous Real-Time 13C Breath Test (BreathID System)

  • M. Inamori
  • H. Iida
  • H. Endo
  • K. Hosono
  • T. Akiyama
  • K. Yoneda
  • K. Fujita
  • T. Iwasaki
  • H. Takahashi
  • M. Yoneda
  • A. Goto
  • Y. Abe
  • N. Kobayashi
  • K. Kubota
  • A. Nakajima
Original Article

Abstract

The aim of this study was to determine whether there is a correlation between aperitif and gastric emptying. Ten healthy male volunteers participated in this randomized, two-way crossover study. Under two conditions (after drinking an aperitif versus not), the 13C breath test was performed for 4 h with a liquid meal (200 kcal/200 ml) containing 100 mg 13C acetate. We used 50 ml of umeshu as the aperitif. This is a traditional Japanese plum liqueur, and contains 7 ml alcohol (14%). In the aperitif group, T 1/2, T lag, and T peak were significantly delayed [T 1/2 (132: 113–174) versus (112: 92–134) (P = 0.0069); T lag (80: 63–94) versus (55: 47–85) (P = 0.0069); and T peak (81: 62–96) versus (54: 34–84) (P = 0.0069), (median: range, aperitif versus control, min)]. Gastric emptying was significantly delayed in the aperitif group as compared with the control group. This study revealed that even a small amount of alcohol such as an aperitif may contribute to delayed gastric emptying.

Keywords

Aperitif Alcohol Umeshu Gastric emptying Breath test 

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • M. Inamori
    • 1
  • H. Iida
    • 1
  • H. Endo
    • 1
  • K. Hosono
    • 1
  • T. Akiyama
    • 1
  • K. Yoneda
    • 1
  • K. Fujita
    • 1
  • T. Iwasaki
    • 1
  • H. Takahashi
    • 1
  • M. Yoneda
    • 1
  • A. Goto
    • 1
  • Y. Abe
    • 1
  • N. Kobayashi
    • 1
  • K. Kubota
    • 1
  • A. Nakajima
    • 1
  1. 1.Gastroenterology DivisionYokohama City University School of MedicineYokohamaJapan

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