Capsule Endoscopy Findings in Celiac Disease
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Capsule endoscopy (CE) is a noninvasive imaging method used to evaluate intestinal mucosa. We aimed to examine intestinal mucosal changes in celiac disease (CD) with CE. Eight untreated patients who had anti-endomysial antibody-positive duodenal biopsy results consistent with CD were included in the study. Villous atrophy, scalloping, fissuring, and mosaic pattern (consistent with CD) were detected in seven patients; one patient was excluded for early meal consumption. No patchy involvement was found in the intestine or distal region of the intestine (ileum) in any of the patients. The common feature of all patients was that villous atrophy, scalloping, fissuring, and mosaic patterns detected in the proximal intestine gradually decreased towards the distal intestine. CE provided no diagnostic contribution to CD when compared with duodenal biopsy. It can be used to show villous atrophy in selected cases and to evaluate the extension of intestinal involvement in CD.
KeywordsCapsule endoscopy Celiac disease Gluten enteropaty Villous atrophy Duodenal biopsy
- 1.Farrell RJ, Kelly CP (2002) Celiac sprue and refractory sprue. In: Feldman M, Friedman LS, Sleisinger MH (eds) Sleisenger and Fordtran’s gastrointestinal and liver disease, 7th edn. WB Saunders, Philadelphia, pp 1817–1841Google Scholar
- 10.Triester SL, Leighton JA, Leontiadis GI et al (2006) A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with non-stricturing small bowel Crohn’s disease. Am J Gastroenterol 101:954–964. doi: 10.1111/j.1572-0241.2006.00506.x PubMedCrossRefGoogle Scholar
- 12.Ersoy O, Sivri B, Arslan S et al (2006) How much helpful is the capsule endoscopy for the diagnosis of small bowel lesions? World J Gastroenterol 28:3906–3910Google Scholar