Author’s Response to Letter to the Editor
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To the Editor,
We appreciate the interest of Drs. Hassall and Owen in our article and are happy to clarify their concerns regarding our report . The questions put forth are made based on their personal observations in management of patients.
Gastroesophageal reflux disease (GERD) and Helicobacter pylori (Hp) are two major research topics of interest to us, hence we routinely evaluate all gastric biopsies for the presence of inflammation, parietal cell hyperplasia and enterochromaffin-cell-like cell (ECL) hyperplasia, Hp density of colonization, and other relevant findings . Stomach biopsies were routinely reviewed by experienced pathologists at Children’s Hospital of Michigan (CHM). When asked specifically about ECL hyperplasia, the Chief of Pathology assured me that it is possible to evaluate for the presence of this finding on routine stains and that special stains are performed for further evaluation if needed. We respect their judgment and expertise regarding this evaluation...
KeywordsEsophagitis Gastroesophageal Reflux Disease Erosive Esophagitis Major Research Topic Refractory GERD
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