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Digestive Diseases and Sciences

, Volume 53, Issue 3, pp 865–866 | Cite as

Rapid Regression of Multiple Gastric Carcinoid Tumors with Hypergastrinemia and Atrophic Gastritis after Renal Transplantation

  • Masaru Odashima
  • Michiro Otaka
  • Mario Jin
  • Youhei Horikawa
  • Tamostu Matsuhashi
  • Reina Ohba
  • Nobuya Mimori
  • Shigeto Koizumi
  • Nobukatsu Kinoshita
  • Taiji Takahashi
  • Sumio Watanabe
Letter

To the Editor

Gastric carcinoid tumors are rare. Nevertheless, when they occur, they are often found in patients diagnosed as having type A gastritis [1]. In patients with type A gastritis, the development of carcinoids and the widespread hyperplasia of enterochromaffin-like cells are related to atrophic changes of fundic mucosa and the trophic action of subsequently raised serum gastrin levels. In the past gastrectomy was the treatment of choice for carcinoid tumors; however, recent reports have shown that multiple gastric carcinoid tumors associated with type A gastritis are indolent and recommend that patients should receive more conservative treatment [1, 2]. We herein present one case where multiple gastric carcinoid tumors with hypergastrinemia and type A gastritis regressed after renal transplantation.

In November 2000, a 51-year-old woman presented with epigastric pain and she received upper gastrointestinal endoscopy in our hospital. Endoscopic examination revealed multiple...

Keywords

Renal Transplantation Gastritis Carcinoid Tumor Endoscopic Examination Atrophic Gastritis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Jordan PH, Barroso A, Sweeney J (2004) Gastric carcinoids in patients with hypergastrinemia. J Am Coll Surg 199:552–555PubMedCrossRefGoogle Scholar
  2. 2.
    Hosokawa O, Kaizaki Y, Hattori M, Douden K, Hayashi H, Morishita M, Ohta K (2005) Long-term follow up patients with multiple gastric carcinoids associated with type A gastritis. Gastric Cancer 8:42–46PubMedCrossRefGoogle Scholar
  3. 3.
    Rindi G, Luinetti O, Cornaggia M, Capella C, Solcia E (1993) Three subtype of gastric argyrophil carcinoid and gastric neuroendocrine carcinoma: a clonicopathologic study. Gastroenterology 104:994–1006PubMedGoogle Scholar
  4. 4.
    Borch K, Ahren B, Ahlman H, Falkmer S, Granerus G, Grimelius L (2005) Gastric carcinoids: Biologic behavior and prognosis after differentiated treatment in relation to type. Ann Surg 242:64–73PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Masaru Odashima
    • 1
  • Michiro Otaka
    • 1
  • Mario Jin
    • 1
  • Youhei Horikawa
    • 1
  • Tamostu Matsuhashi
    • 1
  • Reina Ohba
    • 1
  • Nobuya Mimori
    • 1
  • Shigeto Koizumi
    • 1
  • Nobukatsu Kinoshita
    • 1
  • Taiji Takahashi
    • 1
  • Sumio Watanabe
    • 1
  1. 1.Department of GastroenterogyAkita University School of MedicineAkita city, AkitaJapan

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