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Pregnancy-Associated Liver Disorders

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An Erratum to this article was published on 26 March 2008

Abstract

Liver disorders associated with pregnancy include hyperemesis gravidarum (HG), intrahepatic cholestasis of pregnancy (ICP), preeclampsia, syndrome of hemolysis, elevated liver enzymes and low platelets (HELLP), and acute fatty liver of pregnancy (AFLP). These conditions are relatively common and unique to pregnancy and are more likely to occur at certain terms of gestation specific to each condition. They can be associated with significant maternal and fetal morbidity and mortality. Although managing such patients may be very challenging, spontaneous resolution of the disease occurs shortly after termination of the pregnancy, usually without hepatic sequellae. Early diagnosis and timely treatment is a key to therapeutic success. This article explores the clinical features, pathophysiology, and management of these disorders.

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  1. Department of Medicine, Medical College of Georgia, 1120 15th St., BBR 2540, Augusta, GA, 30912, USA

    Iryna S. Hepburn

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An erratum to this article can be found at http://dx.doi.org/10.1007/s10620-008-0251-9

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Hepburn, I.S. Pregnancy-Associated Liver Disorders. Dig Dis Sci 53, 2334–2358 (2008). https://doi.org/10.1007/s10620-007-0167-9

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