Digestive Diseases and Sciences

, Volume 52, Issue 11, pp 3038–3040 | Cite as

Mesenteric Venulitis: A Rare Etiology of Hematochezia and “Colitis” with Distinctive Colon Pathology

  • Farid Namin
  • Jiten Patel
  • Ivan Damjanov
  • Richard W. McCallum
Case Report


Isolated intestinal vasculitis in the absence of systemic vasculitis can cause ischemia and gastrointestinal bleeding. Mesenteric inflammatory veno-occlusive disease has been reported as a rare cause of intestinal ischemia and GI bleeding. The ischemia mainly affects the right colon and terminal ileum [1]. It may present as a precursor of idiopathic myointimal hyperplasia of the mesenteric veins [1]. This particular entity has also been interpreted as or termed intramural mesenteric venulitis [2]. We report on a case of right and left colonic involvement causing severe necrosis and diffuse GI bleeding throughout the colon. The cause of necrosis and sloughing of colonic mucosa was found to be secondary to intramural mesenteric venulitis, with lymphocytic infiltration and myointimal hyperplasia of the venules of both the superior and the inferior mesenteric veins.

Case report

A 56-year-old white male with no medical history presented to an outside hospital with new and...


Mesenteric venulitis Perivenular myointimal hyperplasia Hematochezia Venulitis Colon 


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Copyright information

© Springer Science + Business Media, Inc. 2007

Authors and Affiliations

  • Farid Namin
    • 1
  • Jiten Patel
    • 1
  • Ivan Damjanov
    • 1
  • Richard W. McCallum
    • 1
  1. 1.Center for Gastrointestinal nerve and muscle Function, Department of Medicine, Pathology and PediatricsKansas University Medical CenterKansasUSA

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